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Hemangiol, Post Marketing Surveillance Study

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Prisijungti Registracija

This study is retrospective, longitudinal, descriptive and observational. Children aged 0 to 1 years hospitalized for introduction of Hemangiol between January 2014 and November 2018 will be included. Patients refuse the use of medical data will be excluded. The main objective is to describe the

Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

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Prisijungti Registracija

PRIMARY OBJECTIVES: I. To reduce therapy associated toxicity for patients with non-metastatic hepatoblastoma (HB) and hepatocellular carcinoma (HCC) without adversely affecting long term outcomes. II. To determine the event-free survival (EFS) in patients with HB whose tumor is completely resected

Nelfinavir and Lenalidomide/Dexamethasone in Progressive Multiple Myeloma

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Prisijungti Registracija

Disease background: MM is a plasma cell tumor. It accounted for an estimated 20,180 new cases of cancer and 11,170 deaths in the United States in 2010. With a prevalence of 23 per 100,000 people, MM is an orphan disease (prevalence <5:10,000). The median age at diagnosis is 60-65 years. Although MM

Combination Chemotherapy, Surgery, and Radiation Therapy in Treating Infants With Neuroblastoma

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Prisijungti Registracija

OBJECTIVES: - Register all children < 12 months of age diagnosed with neuroblastoma. - Evaluate possible prognostic factors in these patients with particular reference to the collection of biological material. - Correlate outcome with factors other than stage in these patients. - Determine criteria

Chemotherapy Before and After Surgery in Treating Children With Wilm's Tumor

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Prisijungti Registracija

OBJECTIVES: - Determine the response rate in children with Wilms' tumor treated with pre-operative chemotherapy. - Compare the response rate in children with intermediate-risk stage II or III Wilms' tumor treated with or without doxorubicin after surgery. - Determine the prognostic significance of

Treatment and Natural History Study of Lymphomatoid Granulomatosis

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Prisijungti Registracija

BACKGROUND: - Lymphomatoid granulomatosis (LYG) is an angiocentric destructive proliferation of lymphoid cells predominantly involving the lungs, skin, kidneys, and central nervous system. - It is divided into three grades, depending on the degree of necrosis and cellular atypia. The grades of

Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia

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Prisijungti Registracija

OBJECTIVES: I. Compare the outcomes in children with higher risk acute lymphocytic leukemia (ALL) treated with postinduction chemotherapy based on marrow response on day 7 of induction therapy: for patients with rapid early response (M1/M2), standard vs intensified consolidation chemotherapy and

Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma

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Prisijungti Registracija

OBJECTIVES: - Compare the value of dexamethasone (DM) vs prednisolone (PRDL) administered during induction therapy, in terms of event-free and overall survival, in children with acute lymphoblastic leukemia (ALL) or lymphoblastic non-Hodgkin's lymphoma (LNHL). - Assess the value of increasing the

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