[Effect of short-term hypoxia on body temperature and lactic acid in the blood of the mouse].

In mice, changes of body temperature and concentration of lactic acid in the blood were studied after three modes of barochamber hypoxia (altitude 8000 m) at the temperatures +10, +20 and +36 degrees C. The greatest drop of body temperature occurred at +10 degrees C, the least one at +36 degrees C. The lactic acid concentration was the greatest (up to 3.6 mM/l) at 2-min ascend and 2-min descend as well as at 2-min ascend, 15-min "altitude", 2-min descend, the temperatures being +20 and +36 degrees C. At 15-time 2-min ascend-descend, the concentration was the least (no more than 2 mM/l). Mechanisms of accelerated adaptation to hypoxia are considered from the standpoint of occurrence of repeated hyperventilation as the result of conditioning to repeated effects of hypoxia.