Latvian
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)
Nutrition and Cancer 2019-Oct

Mexican hawthorn (Crataegus gracilior J. B. Phipps) stems and leaves induce cell death on breast cancer cells.

Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
Saite tiek saglabāta starpliktuvē
Juan Maldonado-Cubas
Exsal Albores-Méndez
Eduardo Martín-Martínez
Cinthya Quiroz-Reyes
Gerardo González-Córdova
Rocio Casañas-Pimentel

Atslēgvārdi

Abstrakts

Diverse molecules with cytotoxic activity against cancer cells have been isolated from the polar extracts of different parts of various hawthorn species that grow around the world. In Mexico, hawthorn (Crataegus gracilior) is popularly consumed, but its content of anticancer substances has never been evaluated. Because antitumor substances have been identified in polar and nonpolar extracts of many plants, we evaluated the cytotoxic activity against breast cancer cells of petroleum ether, ethanol, and water extracts of the leaves and stems of C. gracilior. In contrast to other hawthorn species that contain anti-tumor substances in polar extracts, the petroleum ether extract (but not the ethanol or water extracts) of C. gracilior had cytotoxic properties (IC50 < 50 µg/mL) inducing cell death by apoptosis. Two compounds reportedly having cytotoxic activity were identified by mass spectrometry in the petroleum extract of C. gracilior: β-sitosterol and tocopherol. Results suggest that he cytotoxic and pro-apoptotic effects of the petroleum ether extract of C. gracilior could be exerted by the joint activity of β-sitosterol and tocopherol, possibly in combination with of other minor compounds. Because hawthorn is widely consumed in Mexico and Latin America its potential use as a functional food warrants further investigation.

Pievienojieties mūsu
facebook lapai

Vispilnīgākā ārstniecības augu datu bāze, kuru atbalsta zinātne

  • Darbojas 55 valodās
  • Zāļu ārstniecības līdzekļi, kurus atbalsta zinātne
  • Garšaugu atpazīšana pēc attēla
  • Interaktīva GPS karte - atzīmējiet garšaugus atrašanās vietā (drīzumā)
  • Lasiet zinātniskās publikācijas, kas saistītas ar jūsu meklēšanu
  • Meklēt ārstniecības augus pēc to iedarbības
  • Organizējiet savas intereses un sekojiet līdzi jaunumiem, klīniskajiem izmēģinājumiem un patentiem

Ierakstiet simptomu vai slimību un izlasiet par garšaugiem, kas varētu palīdzēt, ierakstiet zāli un redziet slimības un simptomus, pret kuriem tā tiek lietota.
* Visa informācija ir balstīta uz publicētiem zinātniskiem pētījumiem

Google Play badgeApp Store badge