Zhongguo Zhongyao Zazhi 2007-Sep
[Studies on chemical constituents of in herb Pyrola calliatha].
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Abstrakts
OBJECTIVE
To investigate the chemical constituents of Pyrola calliatha.
METHODS
The chemical constituents were isolated by various column chromatographic methods. The structures were identified by spectral data.
RESULTS
Ten compounds were isolated and identified as chimaphilin (1), uvaol(2), ursolic acid (3), 2beta,3beta,23-trihydroxy-12-ene-28-ursolic acid (4), daucosterol (5), 2alpha,3beta,23,24-tetrahydroxy-12-ene-28-ursolic acid (6), emodin (7), gallic acid (8), monotropein (9), adenosine (10).
CONCLUSIONS
Compounds 2,4,6,7,10 were obtained from this genus for the first time, compounds 5, 9 were obtained from this species for the first time. Antifungal activity of compounds 1-4, 6-9 were evaluated. Compound 1 showed the strong activity.
