Kidney Disease

Hypoxyprobe-1 is a biological marker used to detect oxygen levels in tissue;subjects will receive and intravenous solution for 20 minutes containing 500mg/m^2 two-three hours prior to their standard of care biopsy

Hypoxyprobe-1

Wisconsin Institute for Medical Research (WIMR)

University of Wisconsin Hospital and Clinics

Role of Nox2 in CNI-induced Renal Fibrosis

The Role of Nox2 in CNI-Induced Renal Fibrosis

The Nox2 protein will be determined in subjects who are potentially have CNI nephrotoxicity

12 months after a baseline BOLDMRI, subjects will have a second BOLD MRI in order to determine whether there is increased oxygenation

University of Wisconsin, Madison

Nephropathy

Oxidative Stress

NS 500ml + Glutathione 1.8g intravenously guttae 1-1.5ml/kg per hour,30 minutes before and during coronary angiography

Glutathione

NS 500ml intravenously guttae 1-1.5ml/kg per hour,30 minutes before and during coronary angiography

saline

Department of cardiology and nephrology,Huashan Hospital

Polymorphism of Oxidative Stress Genes in the Pathogenesis and Antioxidant Prevention of Contrast Induced Nephropathy

Polymorphism of Oxidative Stress Relative Genes in Contrast Medium Induced Nephropathy:Implications in the Pathogenesis and the Effect of Antioxidant prevention-a Prospective,Randomized,Controlled Study

CIN is defined as a relative increase of the serum creatinine by 25% or as an absolute increase of 0.5mg/dl(44.2umol/l) from baseline within 48-72h after contrast exposure.

catalase/hypoxia

Role of Nox2 in CNI-induced Renal Fibrosis

Polymorphism of Oxidative Stress Genes in the Pathogenesis and Antioxidant Prevention of Contrast Induced Nephropathy

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