cyclooxygenase/atrofija

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Early Treatment Versus Expectant Management of PDA in Preterm Infants

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non_invasive_aICP_Tumor

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Primary brain tumors in adults are less common than metastatic tumors. The most frequent are glioblastoma multiforme, metastases, anaplastic astrocytoma, meningioma, pituitary tumors and vestibular schwannoma. 70% of the tumors in adults are supratentorial. The most infratentorial tumors are

Tecfidera Diffusion Tensor Imaging

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Multiple sclerosis (MS) is a central nervous system (CNS) autoimmune disorder characterized by chronic inflammation, axonal demyelination, and neuronal degeneration. The complex pathophysiology of MS is mediated by autoreactive T cells that ultimately invade and attack the CNS by traversing the

Efficacy and Safety of Shea Nut Oil in Hemophilic Arthropathy

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Hemophilia is an X-linked recessive bleeding disorder caused by a deficiency of coagulation factor VIII (hemophilia A) or IX (hemophilia B). Severe hemophilia patients may have frequent spontaneous bleeding episodes such as joint and muscle bleeding. Repeated joint bleeding leads to chronic

Oxidative Damage and Antioxidant Mechanisms in COPD

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Introduction Lung is a particularly important organ because of its interface with the environment. The environmental pollutants and endogenous reactive oxygen metabolites from inflammatory cells exert substantial pathological effects on the lung cells [1]. Oxidative stress (OS) is a major factor

Cognitive Impact of Paracetamol in Healthy Volunteers

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Paracetamol impact on cognitive processes has been until recently little studied in literature that presents conflicting results. Some authors do not describe any cognitive performance change (Bradley and Nicholson, 1987) but more recent studies (Ishida et al., 2007) report an interesting

Role of Minocycline in First Episode Psychosis

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Background: There is increasing clinical, neuropsychological and imaging evidence that schizophrenia involves a progressive process at the time of the first episode and later in life. However, it is not clear which systems are affected nor in which parts of the brain. In two Stanley first episode

Safety and Efficacy of TAK-715 in Subjects With Rheumatoid Arthritis

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Rheumatoid arthritis affects approximately 1% of the adult population, and is a chronic, progressive disease characterized by synovial inflammation. The resulting inflammation leads to destruction of the synovium and surrounding joint tissues, which can result in cartilage destruction, bone erosion

Efficacy Study of FANG(30) for Active Rheumatoid Arthritis in Adult Patients

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Introduction: Rheumatoid Arthritis (RA) is a common rheumatic disease characterized by pain, inflammation and reduction in joint function. Hands and feet are the most commonly affected joints and pain is the cause that brings patients with RA to search for medical assistance. Factors causing pain

Flavocoxid, A Plant-Derived Therapy, for the Treatment of Knee Osteoarthritis

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OA is a leading chronic disease in older adults and is characterized by degeneration of articular cartilage of the joints in hands, spine, knees, and hips. In joints, tissue injury and pain are caused by the conversion of arachidonic acid to such inflammatory compounds as cyclooxygenases-1 and -2

Celecoxib to Treat Macular Degeneration in Patients Receiving Photodynamic Therapy

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Age-related macular degeneration (AMD) represents the most common cause of blindness in patients over the age of 60. The major cause of vision loss in this disease is due to the development of choroidal neovascularization. Several clinical trials have shown that eyes with predominately

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