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Lappuse 1 no 92 rezultātiem
Method and structure for inhibiting activity of serine elastases
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
BACKGROUND ART
Elastase is a general term that describes a group of protease enzymes that have the ability to degrade elastin. Elastin is the primary extracellular matrix protein that confers elastic qualities to a variety of tissues including the lung, skin and blood vessels. Different proteases
Tetrazolyl derivatives of .beta.-lactams useful as elastase inhibitors
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
BACKGROUND OF THE INVENTION
We have found that tetrazolyl derivatives of .beta.-lactams such as cephalosporins and penicillins are potent elastase inhibitors and therefore useful anti-inflammatory/antidegenerative agents.
Proteases from granulocytes and macrophages have been reported to be
Tetrazolyl derivatives of beta-lactams useful as elastase inhibitors
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
BACKGROUND OF THE INVENTION
We have found that tetrazolyl derivatives of .beta.-lactams such as cephalosporins and penicillins are anti-inflammatory/antidegenerative agents. potent elastase inhibitors and therefore useful
Proteases from granulocytes and macrophages have been reported to be
Bethalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
BACKGROUND OF THE INVENTION
We have found that a group of new substituted azetidinones are potent elastase inhibitors and therefore are useful anti-inflammatory and antidegenerative agents.
Proteases from granulocytes and macrophages have been reported to be responsible for the chronic tissue
Novel betalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
BACKGROUND OF THE INVENTION
We have found that a group of new substituted azetidinones are potent elastase inhibitors and therefore are useful anti-inflammatory and antidegenerative agents.
Proteases from granulocytes and macrophages have been reported to be responsible for the chronic tissue
Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
This invention relates to substituted bicyclic dihydropyrimidinones of formula 1
##STR00002## and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary,
Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
This invention relates to substituted bicyclic dihydropyrimidinones of formula 1
##STR00002## and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary,
Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
This invention relates to substituted bicyclic dihydropyrimidinones of formula 1
##STR00002## and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary,
Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
FIELD OF THE INVENTION
This invention relates to substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and
Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
FIELD OF THE INVENTION
This invention relates to substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and
Substituted pyridones and pyrazinones and their use as inhibitors of neutrophil elastase activity
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
FIELD OF THE INVENTION
This invention relates to substituted 2-pyridones and pyrazinones of formula 1
##STR00002## and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of
Use of a sophorolipid to provide free radical formation inhibiting activity or elastase inhibiting activity
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
This application is the U.S. national stage entry under 35 U.S.C. 371 of PCT/FR95/00768, filed Jun. 12, 1995.
The present invention concerns a novel use of sophorolipids.
The present invention also concerns cosmetic or dermatological compositions.
More particularly, the present invention concerns
Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
BACKGROUND OF THE INVENTION
We have found that sulfones of substituted cephalosporins are potent elastase inhibitors and therefore are useful anti-inflammatory/antidegenerative agents.
Proteases from granulocytes and macrophages have been reported to be responsible for the chronic tissue destruction
Substituted cephalosporin sulfoxides as anti-inflammatory and antidegenerative agents
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
BACKGROUND OF THE INVENTION
We have found that sulfoxides of substituted cephalosporins are potent elastase inhibitors and therefore are useful anti-inflammatory/antidegenerative agents.
Proteases from granulocytes and macrophages have been reported to be responsible for the chronic tissue
Substituted azetidinones as anti-inflammatory and antidegenerative agents
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
BACKGROUND OF THE INVENTION
We have found that a group of new substituted azetidinones are potent elastase inhibitors and therefore are useful anti-inflammatory/antidegenerative agents.
Proteases from granulocytes and macrophages have been reported to be responsible for the chronic tissue
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