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Sildenafil in COVID19

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Ielogoties Reģistrēties

Perfusion anomalies, namely hypoperfusion of healthy lung and vasoplegia with hyperperfusion of diseased lung areas, have been recently described amongst patients with COVID19. In this triple-blind pilot randomised trial, adult patients with high clinical suspicion of SARS-CoV2 infection and

Analysis and Comparative Evaluation of Aortic Calcium by Computed Tomography and Histopathology in Patients With Aortic Stenosis

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Ielogoties Reģistrēties

1. Title Analysis and comparative evaluation of aortic calcium by computed tomography and histopathology in patients with aortic stenosis. 2. Background. Calcified aortic valve disease (CAVD) was initially considered to be a passive degeneration of the extracellular matrix (EM). Recent studies have

The Exercise, Arterial Modulation and Nutrition in Youth South Africa Study

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Ielogoties Reģistrēties

Background: The current global widespread incidence of obesity and early cardiovascular deterioration are two of the most important future health care challenges. Physical inactivity and its associated unhealthy dietary intake among adolescents are of great concern, especially in a South African

Treatment of Calculous Pyonephrosis With 0.5% Iodophors for I-stage PCNL

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Ielogoties Reģistrēties

Calculous Pyonephrosis is a special type of urinary tract calculi, which is also common in clinical practice. If pyonephrosis is not treated in time, it will have a serious impact on the kidney function. It can lead to renal failure and atrophy in the late stage. It can also cause acute peritonitis

Effect of Dietary Nitrate Ingestion in Heart Failure

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Ielogoties Reģistrēties

Background: Heart failure (HF) affects 1-2% of those under 70 years, and 10-20% of those over 70 years in developed countries; approximately 900,000 people in the UK suffer with HF. Despite several promising pre-clinical targets, clinical translation has been disappointing, with very few successful

Neuroactive Steroids in Acute Ischemic Stroke

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Ielogoties Reģistrēties

Acute Ischemic Stroke (AIS) is one of the main causes of functional deterioration all over the world. Thus, 26% of patients older than 65 years still show limitations of daily activities 6 months after AIS, and 46% of these patients present cognitive deficiency of variable severity. AIS impose a

Effects of Melatonin to Reduce Nocturnal Hypertension in Patients With Neurogenic Orthostatic Hypotension

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Ielogoties Reģistrēties

Neurogenic orthostatic hypotension (NOH) is a debilitating condition associated with reduced quality of life, impaired function and is also an independent predictor of mortality(Bendini et al., 2007; Cordeiro et al., 2009; Rose et al., 2006). NOH is clinically defined as a sustained reduction in

Hyperbaric Oxygen Therapy in Patients With Chronic Stable Ischemic Heart Disease: An Option for Therapeutic Angiogenesis?

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Ielogoties Reģistrēties

Ischemic heart disease is the leading cause of mortality in the United States and second most common in Israel. Myocardial ischemia prevails when imbalance between oxygen demand and delivery to the myocardium occurs: due to increased oxygen demand beyond what can be delivered by increased coronary

Peripheral Perfusion and Oxygenation in Areas of Risk of Skin Integrity Impairment Exposed to Pressure Patterns.

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Ielogoties Reģistrēties

Sample: the preclinical phase will be conducted in 20 healthy volunteers enrolled in the Faculty of Health Sciences of the University of Malaga. Clinical phase will take place in 12 subjects admitted to acute hospitalization in 'Costa del Sol' Health Agency and 12 subjects admitted to nursing homes

Oral Nitrite for Older Heart Failure Patients

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Ielogoties Reģistrēties

Heart failure (HF) is epidemic with aging and prevalence of HF is steadily increasing as the population of older adults expands. Despite the fact that age always stands out as a leading risk factor for HF incidence as well as for poor HF prognosis, few HF trials focus specifically on aging

Peroral Endoscopic Myotomy (POEM) For The Treatment Of Achalasia: A Registry

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Ielogoties Reģistrēties

Our institution performs therapeutic Interventional Endoscopy in around 700-1000 patients a year. We come across several patients with esophageal disorders, including esophageal cancer and Achalasia. Achalasia is an uncommon esophageal motility disorder caused by the inability of the lower

Botulinum Toxin Injection to Treat Diffuse Esophageal Spasm

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Ielogoties Reģistrēties

Patients are selected on the basis of a clinical diagnosis of diffuse esophageal spasm, based on endoscopy and manometry. This is a sham-controlled cross-over study of injection of botulinum toxin or saline, in randomized order, in the distal esophagus. All patients have undergone esophageal

Evaluation of Corneal Hysteresis and Corneal Resistance Factor After Corneal Cross-linking for Keratoconus

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Ielogoties Reģistrēties

Human Papillomavirus on Oral Tissue, Saliva and Serum

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Ielogoties Reģistrēties

This study will made at the buccal cancer center of UNESP and involved forty patients (n = 40) and forty controls. Serum samples, oral swabs and saliva will collect at the date of diagnosis before therapy and will store at -80 ºC until analysis. Formalin-fixed paraffin-embedded oral squamous cell

Phase I Trial of Inhaled Nitric Oxide to Treat Acute Pulmonary Embolism

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Ielogoties Reģistrēties

We propose to enroll a total of 25 patients with recently diagnosed pulmonary embolism. Inclusion criteria will include moderate to severe shortness of breath as rated by the patient on a standard scoring system, a systolic blood pressure of >89 mm Hg unless the patient has a known prior history of

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