24 Patient will receive Curcumin (CC) pills, within 24 hours post-operatively (as long as they are able to take oral medication). It will then be continued TID

24 Patient will receive Placebo pills, within 24 hours post-operatively (as long as they are able to take oral medication. It will then be continued TID.

Hematoma, Subdural, Chronic

Curcumin (turmeric extract), over the counter supplement (1 capsule/three times a day). According to the Company, each capsule contains: 270 mg of pure curcuminoids (curcumin) and 3 mg of black pepper extract. Recommended serving size is 3 capsules per day in total, the patients will receive 810 mg of pure curcumin and 9 mg of black pepper extract (peperine/BioPerine) per day.

Curcumin Pill

The placebo pill is a vegetarian cellulose capsule, with cellulose powder inside. The composition is cellulose and magnesium stearate.

Placebo pills

University of New Mexico Health Sciences center

Curcumin/Turmeric as a Treatment for Patients With Subdural Hematomas Recurrence

Clinical Action of Curcumin/Turmeric in Chronic Subdural Hematoma Recurrence

Change of the total hematoma cavity volume compared to post-subdural drain removal to volumes of less than 80 cc in post-surgical patients

Change rate of persistent or recurrent neurological symptoms

University of New Mexico

This is an experimental study, each consented subject will be instructed that he/she will be randomized to either the placebo group or the curcumin group.

This is a double-blinded, randomized placebo-controlled pilot study. The patients, neurosurgeons, nurses and clinical coordinators will be blinded except for the research pharmacists who will keep a key linking a code # on a bottle handed to the clinical coordinator and the patient's medical record number (MRN #). The pill bottles handed to the clinical coordinator will be identical for placebo and CC.

piper/kariess

Curcumin/Turmeric as a Treatment for Patients With Subdural Hematomas Recurrence

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