prostatic hyperplasia/hypoxia

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[The role of detrusor hypoxia in the pathogenesis of urination disorders in patients with benign prostatic hyperplasia].

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Ielogoties Reģistrēties

The aim of the study was to clarify the role of hypoxia of detrusor as a component of aging in establishment of urination disorders in patients with benign prostatic hyperplasia (BPH). A total of 54 patients were examined. Whether the capacity of detrusor to absorb oxygen was affected or not was

Finasteride effects on hypoxia and angiogenetic markers in benign prostatic hyperplasia.

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Ielogoties Reģistrēties

OBJECTIVE To assess the effects of finasteride on angiogenetic and hypoxia markers in benign prostatic hyperplasia. METHODS A total of 178 patients aged 51 to 85 years (mean 68.7) with benign prostatic hyperplasia and awaiting transurethral prostate resection were prospectively randomized into a

Hypoxia-inducible factor 1α (HIF-1α) mediates the epithelial-mesenchymal transition in benign prostatic hyperplasia.

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Ielogoties Reģistrēties

Epithelial-mesenchymal transition (EMT) based cancer cell invasion and metastasis has been thoroughly studied in prostate cancer. It was well known that EMT markers which have been found in benign prostatic hyperplasia (BPH) tissues, but system descriptions have not been

[Role of blood supply disturbance and tissue hypoxia in the development of bladder dysfunction in bladder outlet obstruction caused by the prostatic adenoma].

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Ielogoties Reģistrēties

An immunohistochemical assessment of hypoxia in prostate carcinoma using pimonidazole: implications for radioresistance.

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Ielogoties Reģistrēties

OBJECTIVE To investigate the presence of hypoxia in human prostate carcinoma by using pimonidazole immunohistochemical labeling in radical prostatectomy specimens. METHODS Forty-three patients (median age, 69 years; range, 49-83 years) with localized prostate adenocarcinoma received 0.5 gm/m2 i.v.

[Clinical analysis of postoperative delirium in elderly patients with benign prostatic hyperplasia].

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Ielogoties Reģistrēties

OBJECTIVE To study the influential factors leading to postoperative delirium in elderly patients with benign prostatic hyperplasia(BPH). METHODS For 198 elderly postoperative BPH patients in our hospital, the clinical parameters including age, hypoxemia, postoperative pain, and sleep reduction were

Increased risk of benign prostate hyperplasia in sleep apnea patients: a nationwide population-based study.

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Ielogoties Reģistrēties

BACKGROUND Sleep apnea (SA) is a common sleep disorder characterized by chronic intermittent hypoxia (IH). Chronic IH induces systemic inflammatory processes, which can cause tissue damage and contribute to prostatic enlargement. The purpose of this study was to evaluate the association between

[The mechanism of action of the alpha-adrenoblocker prazosin on bladder function in patients with benign prostatic hyperplasia].

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Ielogoties Reģistrēties

Prazosin treatment effects were evaluated in two groups of patients with benign prostatic hyperplasia (BPH). 10 patients of group 1 have previously undergone epicystostomy for acute urine retention. They received prazosin for 7 days 5 mg/day. 9 patients of group 2 had no direct indications for

[Reserve capacities of blood coagulation and total lytic activities in patients with benign prostatic hyperplasia].

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Ielogoties Reģistrēties

Prior to and after the double local arm hypoxia test, whole blood thromboelastography under lowered contact activation was used to examine hemostasis and total blood lytic activity in 27 males aged 59-68 years who had moderate benign prostatic hyperplasia (BPH) as assessed by the International

Increased growth factor production in a human prostatic stromal cell culture model caused by hypoxia.

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Ielogoties Reģistrēties

BACKGROUND Local hypoxia may be one of the triggers of embryonic reawakening of the stroma and subsequent hyperplastic growth in the prostate. Using a cell culture model of human prostatic stromal cells, we investigated the effects of hypoxia on activation of hypoxia-inducible factor 1 (HIF 1) and

Does the prostatic vascular system contribute to the development of benign prostatic hyperplasia?

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Ielogoties Reģistrēties

Benign prostatic hyperplasia (BPH) is a disease condition characterized by abnormal prostate growth in conjunction with distinct lower urinary tract symptoms. This paper considers the extent to which the prostatic vascular system contributes to normal prostate growth control as well as whether

Analysis of hypoxia-associated gene expression in prostate cancer: lysyl oxidase and glucose transporter-1 expression correlate with Gleason score.

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Ielogoties Reģistrēties

Prostate cancer cells exist under hypoxic conditions. Hypoxia has a detrimental effect on the efficacy of treatment and final outcome in patients with prostate cancer. There have been a large number of endogenous markers of hypoxia described previously across a range of cancer types, both in vitro

[Efficacy of Kangshuailing Gao on benign prostatic hyperplasia in rats].

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Ielogoties Reģistrēties

UNASSIGNED To investigate the effect of Kangshuailing Gao (KG) on benign prostatic hyperplasia (BPH) in rats and its action mechanisms. METHODS Fifty BPH model rats were randomized into five groups of equal number, BPH model control, finasteride control, and high-, medium- and low-dose KG, to be

Qianliening capsule inhibits benign prostatic hyperplasia angiogenesis via the HIF-1α signaling pathway.

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Ielogoties Reģistrēties

Angiogenesis plays an important role in the progression and development of benign prostatic hyperplasia (BPH), and has become a promising target for BPH treatment. The hypoxia-inducible factor-1α (HIF-1α) signaling pathway promotes the process of angiogenesis, contributing to the growth and

[Pathophysiology and therapy of benign prostatic hyperplasia].

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Ielogoties Reģistrēties

Benign prostatic hyperplasia (BPH) and benign prostatic enlargement (BPE) are among the most frequent medical disorders of elderly men and cause a number of annoying symptoms of the lower urinary tract (LUTS), leading to reduced quality of life and severe complications, including acute urinary

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