thymidine/aptaukošanās

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Lappuse 1 no 116 rezultātiem

Decreased level of thymidine in the serum of obese strain (OS) chickens with spontaneous autoimmune thyroiditis.

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Ielogoties Reģistrēties

We have previously shown that normal chicken serum (NCS) is able to interfere with the IL 2 promoted incorporation of DNA precursors into T lymphoblasts and that serum derived from autoimmunity prone Obese strain (OS) chickens is deficient in this respect. This "defect in non-specific suppression"

In vitro incorporation of thymidine-H3 in the pancreas of normal and obese-hyperglycemic mice.

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Ielogoties Reģistrēties

Adipose tissue hyperplasia and hyperinsulinemia on Zucker obese female rats: a developmental study.

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Ielogoties Reģistrēties

Obese female Zucker rats show persistent increases in fat cell number compared to lean female Zucker rats from 5 to 52 wk of age. The hyperplastic obesity of the Zucker rat is also accompanied by fat cell hypertrophy and elevated plasma immunoreactive insulin (IRI). Average adipocyte size reaches a

Morphology and cell dynamics of adipose tissue in hypothalamic obese mice.

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Ielogoties Reģistrēties

Morphological and cell kinetic characteristics of the epididymal adipose tissue of obese mice, induced by monosodium glutamate (MSG), were examined in comparison to those of normal mice. Mice treated with MSG for 5 postnatal days became obese after 8 wk of age; adipocytes of the MSG-treated mice

Serological thymidine kinase 1 is a biomarker for early detection of tumours--a health screening study on 35,365 people, using a sensitive chemiluminescent dot blot assay.

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Ielogoties Reģistrēties

Serological thymidine kinase 1 (STK1) is a reliable proliferation marker for prognosis, monitoring tumour therapy, and relapse. Here we investigated the use of STK1 in health screening for early detection of pre-malignant and malignant diseases. The investigation was based on 35,365 participants in

Impaired immunity in obesity: suppressed but reversible lymphocyte responsiveness.

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Ielogoties Reģistrēties

Although obese people have been reported to have a higher incidence of infections and some types of cancer, the immunocompetence of obese subjects remains poorly understood. To investigate whether obesity affects immunity, we studied obese subjects (BMI > 30 kg/m2) whose health was uncomplicated by

Morphological and cell proliferative study on the growth of visceral organs in monosodium L-glutamate-treated obese mice.

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Ielogoties Reģistrēties

The growth pattern of visceral organs was investigated in monosodium L-glutamate (MSG)-treated obese mice with hypothalamic lesions. Male Jcl-ICR strain mice were subcutaneously injected with MSG, 2 mg/g of body weight daily, for five days after birth. The MSG-treated mice became obese after 4 weeks

[Effects of pravastatin in prevention of diabetes and mechanism thereof: experiment with non-obese diabetic mice].

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Ielogoties Reģistrēties

OBJECTIVE To explore the effects of pravastatin in prevention of diabetes and mechanisms thereof. METHODS 1183 to 4-week-old female non-obese diabetic (NOD) mice were randomly divided into 4 groups: control group (n = 30), fed with regular diet, low-dose pravastatin group (n = 29), fed with 1 mg

n-3 fatty acids modulate T-cell calcium signaling in obese macrosomic rats.

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Ielogoties Reģistrēties

OBJECTIVE We investigated the effects of a diet containing EPAX-7010, rich in PUFAs such as eicosapentaenoic acid [20:5(n-3)] and docosahexaenoic acid [22:6(n-3)], i.e., a PUFA/EPAX regimen, on T-cell activation in diabetic pregnant rats and their obese pups. METHODS Mild hyperglycemia in pregnant

Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity.

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Ielogoties Reģistrēties

Central obesity is associated with increased morbidity and mortality. Preadipocyte proliferation and differentiation contribute to increases in adipose tissue mass, yet the mechanisms that underlie these processes remain unclear. Patients with glucocorticoid excess develop a reversible form of

Effect of caloric restriction on colonic proliferation in obese persons: implications for colon cancer prevention.

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Ielogoties Reģistrēties

Dietary intervention to prevent colon cancer is a major health issue. At present it is not clear which dietary factors modify colon cancer risk. Caloric restriction reduces the incidence of many spontaneous and carcinogen-induced tumors in rodents, but its role in human carcinogenesis is unknown.

The modifying effect of C-reactive protein gene polymorphisms on the association between central obesity and endometrial cancer risk.

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Ielogoties Reģistrēties

BACKGROUND Obesity is a major risk factor for endometrial cancer. Obesity, particularly central obesity, is considered as a systemic inflammatory condition and is related strongly to insulin resistance. C-reactive protein (CRP) is the most recognized biologic marker of chronic systematic

Effect of regular circus physical exercises on lymphocytes in overweight children.

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Ielogoties Reģistrēties

Obesity associated with a sedentary lifestyle can lead to changes in the immune system balance resulting in the development of inflammatory diseases. The aim of this study was to compare lymphocyte activation mechanisms between overweight children practicing regular circus physical exercises with

Increased SMC proliferation after endothelial injury in hyperinsulinemic obese Zucker rats.

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Ielogoties Reģistrēties

The long-term effect of long-lasting hyperinsulinemia on aortic smooth muscle cell (SMC) proliferation after endothelial injury was investigated using the obese Zucker rat model, which is characterized especially by early spontaneous development of hyperinsulinemia and insulin resistance. SMC

DNA replication in transplanted and endogenous pancreatic islets of obese-hyperglycemic mice at different stages of the syndrome.

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Ielogoties Reģistrēties

It was the aim of the present study to examine, at different stages of the obese-hyperglycemic syndrome, rates of islet-cell DNA replication in endogenous pancreatic and grafted islets of such mice. For this purpose obese-hyperglycemic mice were given an islet transplant prepared from lean mice

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