tuberculosis/nikotīns

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BCG Vaccine for Health Care Workers as Defense Against COVID 19

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Study design: A placebo-controlled adaptive multi-center randomized controlled trial. Study population: High risk HCW with direct patient contacts, defined as physician assistants, respiratory therapists, nurses, physicians or other HCWs working at emergency rooms, ICUs and in locations within

Roflumilast in Non-CF Bronchiectasis Study (2019)

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In a 4-week crossover study in 38 patients with COPD, roflumilast 500μg daily significantly reduced sputum absolute neutrophil count, IL-8 and neutrophil elastase compared with placebo treatment. Interestingly, the mechanism of anti-neutrophilic inflammation with roflumilast treatment in patients

Alcohol Reduction Among People With TB and HIV in India

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Ielogoties Reģistrēties

In 2017, over 10 million people worldwide developed tuberculosis disease (TB), with 9% of cases among people with HIV (PWH). In that same year, there were 1.6 million deaths from TB, with 300,000 among PWH. The highest incidence of TB is in India, accounting for 27% of all new cases globally, with

Artificial Inteligent for Diagnosing Drug-Resistant Tuberculosis

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PROCEDURE 1. Under the permission granted by the study centers, the team will obtain the medical records of all eligible cases within the past 5 years 2. The investigators then collect the information of interest variable/parameter which obtained by history taking and further examinations and also

Isolation of Circulating Pulmonary Cells in COPD and Its Relationship With Clinical Relevant Outcomes (IbICEnCa)

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1. HYPOTHESIS 1.1. MAIN HYPOTHESIS. - CPCs isolation is frequent in COPD patients and also (to a lower level) in smokers without COPD but is not possible in healthy non-smokers. - CPCs isolation is related to important clinical outcomes in COPD. 1.2. SECONDARY HYPOTHESIS. - CPCs isolation in COPD is

COPD Readmissions Prediction- ReCOPD Project

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DESIGN: A prospective observational cohort study with a nested case control study, with one year follow-up from index hospital admission. SETTING: Multicenter and multidisciplinary study taking part the following hospitals: Costa del Sol Hospital (Andalusia), Nuestra Señora de la Candelaria

Volatiles in Breath and Headspace Analysis - Diagnostic Markers

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Study propose to explore a novel approach for the diagnosis and monitoring of diseases. The approach is based on the detection of volatile organic compounds (VOCs) that are emitted from the cells and detected directly from tissue, such as skin, surgery material, blood as well as from exhaled

Prevention of Tuberculosis in Prisons

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Despite being a known disease of mankind over 9000 years, tuberculosis (TB) is still a major public health problem in developing countries, mainly due to so-called highly endemic sites, such as prisons. It is Infectious disease, with airborne transmission, TB can present both the active or latent

Phenotyping the Chronic Respiratory Diseases (CRD) in Ho Chi Minh City, Vietnam

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A Controlled Smoking Cessation Trial and Prospective Cohort Study of Tuberculosis (TB) Treatment Outcomes

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A Smoking Cessation Trial in HIV-infected Patients in South Africa

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Tobacco use is estimated to be responsible for over 5 million deaths globally every year and HIV/AIDS kills 2 million worldwide, with persons living in the developing world especially at risk. However, the association between tobacco use and HIV is not clearly understood. The introduction of highly

Intensive Smoking-cessation Intervention Versus Smoking-cessation Advice in Smear-positive Patients With Pulmonary Tuberculosis

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Ielogoties Reģistrēties

No clinical trials have been done to determine if the cessation of smoking has any influence on outcome in tuberculosis patients. In particular, if smoking cessation leads to a higher rate of sputum culture-conversion at 2 months, TB transmission rates should be reduced. Such targeted

The Incidence of Nontuberculous Mycobacterial Pulmonary Infection in Bilateral Bronchiectasis and Bronchiolitis

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Ielogoties Reģistrēties

Study Population During the study period helical thin-section thoracic CT scans will obtained in patients in whom a diagnosis of bronchiectasis was known or who were suspected of having bronchiectasis on the basis of clinical symptoms and signs of a chronic cough and sputum production. One chest

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