Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression 1989-Sep
Echocardiographic evaluation of vagolytic effects of hyoscine butylbromide in paediatric halothane anaesthesia.
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The effects of vagolysis with hyoscine butylbromide on left ventricular function were evaluated by echocardiography during halothane anaesthesia in children. Echocardiography showed deterioration of the following values after halothane induction; pre-ejection period, systolic time interval, left ventricular shortening fraction and ejection fraction. The first two values were improved by vagolysls with hyoscine butylbromide. However, relatively rate-independent indices, i.e. left ventricular shortening fraction and ejection fraction, still remained depressed even after vagolysis with hyoscine butylbromide. This implies that halothane-induced myocardial depression can only be partially antagonized by vagolysis.
