Promethazine 25 mg/mL in Pluronic Lecithin Organogel for Nausea and Vomiting in a Pediatric Patient: A Case Report.

Nausea and vomiting, especially in pediatric patients, can cause dehydration, the treatment for which may require hospitalization . In patients who resist rectal dosage forms or are unable to tolerate oral medications, a compounded transdermal gel containing an antiemetic agent such as promethazine can provide effective relief without producing major adverse effects. In this case report, the treatment of severe nausea and vomiting caused by acute viral gastritis in a pediatric patient is described, and a formulation for an effective transdermal compound is provided.