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acetic acid/inflammation
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Anti-inflammatory and analgesig thiophene acetic acid derivatives, compositions, and method of use therefor
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Related compounds are described in French patent No. 2,346,348 and Chem. Abs., Vol. 95 No. 7 (1981) p. 689, No. 61895d.
OBJECTS OF THE INVENTION
It is an object of the invention to provide the novel compounds of formula I and their salts and a novel process and intermediates for their
Acetic acid derivative having choleretic and anti-inflammatory activity
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This invention relates to a pharmacologically active acetic acid derivative and is concerned with its use as a choleretic and anti-inflammatory agent.
The acetic acid derivative which in accordance with the invention has been found to have both choleretic activity and anti-inflammatory activity is
2,3,4,9-tetrahydro-1H-carbazole acetic acid derivatives, composition and use as anti-inflammatories
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BACKGROUND OF THE INVENTION
a. Field of Invention
This invention relates to tricyclic acetic acid derivatives, to their preparation and use, and to intermediates used for their preparation.
More specifically, this invention relates to tricyclic acetic acid derivatives in which the tricyclic portion
Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid esters used for treating inflammation, pain or pyrexia
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This invention relates to novel compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid derivatives, or salts or esters thereof, and the use thereof in the treatment of inflammation, pain and pyrexia.
The compositions of this invention consist essentially of the combination of a
Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof
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This invention relates to novel compositions useful as anti-inflammatory, analgesic, anti-pyretic and anti-pruritic agents. It also relates to novel methods for treating conditions marked by inflammation, pain, pyrexia, and pruritus. It further relates to novel compounds which are thus useful and to
Substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives useful in the treatment of autoimmune and inflammatory disorders
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FIELD OF THE INVENTION
The present invention relates to certain substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives of Formula (Ia) and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the S1P1 receptor.
Substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives useful in the treatment of autoimmune and inflammatory disorders
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FIELD OF THE INVENTION
The present invention relates to certain substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives of Formula (Ia) and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the S1P1 receptor.
Substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives useful in the treatment of autoimmune and inflammatory disorders
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FIELD OF THE INVENTION
The present invention relates to certain substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives of Formula (Ia) and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the S1P1 receptor.
Novel thiophene-acetic acids
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OBJECTS OF THE INVENTION
It is an object of the invention to provide the novel thiophene acetic acid derivatives of formulae I and II.
It is another object of the invention to provide a novel process for the preparation of the thiophene acetic acid derivatives of formulae I and II.
It is an
Susbtituted fused tetrahydrocarbazole acetic acid derivatives
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This invention relates to novel tetrahydrocarbazole acetic acid derivatives possessing lipoxygenase inhibitor and/or cyclooxygenase inhibitory activity which are useful as anti-inflammatory and antiallergic agents. For instance, they exhibit analgesic and anti-inflammatory activity at dose levels
.omega.-(1,3-Dithiolan-2-imino) substituted acetic acids
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FIELD OF THE INVENTION
This invention relates to novel heterocyclic derivatives of acetic acid and their preparation and to their use as anti-inflammatory agents.
SUMMARY OF THE INVENTION
I have discovered that certain heterocyclic derivatives of acetic acid possess useful antibacterial and
Halo-substituted 1-loweralkyl-5-aroylpyrrole-2-acetic acid compounds
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DESCRIPTION OF THE INVENTION
This invention relates to novel halo-substituted 1-loweralkyl-5-aroylpyrrole-2-acetic acid compounds, and particularly to compounds having the following formulas: ##STR1## wherein X is a member selected from the group consisting of chloro and bromo, R is loweralkyl, R'
Substituted fused tetrahydrocarbazole acetic acid derivatives, compositions and use
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This invention relates to novel tetrahydrocarbazole acetic acid derivatives possessing lipoxygenase inhibitory and/or cyclooxygenase inhibitory activity which are useful as anti-inflammatory and antiallergic agents. For instance, they exhibit analgesic and anti-inflammatory activity at dose levels
Preparation of 2,3,4,9-tetrahydro-1H-carbazole acetic acid derivatives
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BACKGROUND OF THE INVENTION
1. Field of Invention
This invention relates to tricyclic acetic acid derivatives, to their preparation and use, and to intermediates used for their preparation.
More specifically, this invention relates to tricyclic acetic acid derivatives in which the tricyclic portion
2-(6-Substituted-2'-naphthyl) acetic acid derivatives and the salts and esters thereof
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This invention relates to novel 2-(6'-substituted-2'-naphthyl)acetic acid derivatives and salts and esters thereof which are useful as anti-inflammatory, analgesic and anti-pyretic agents.
The compounds of this invention are the carboxylic acids and carboxylic acid esters represented by the
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