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fucose/рак

Врската е зачувана во таблата со исечоци
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Process for determining tumor-associated glycolinkage

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BACKGROUND OF THE INVENTION The present invention relates to a process for determining tumor-associated glycolinkage (hereunder referred to as TAG) in the body fluid of mammals, more particularly, TAG including glycoproteins, glycopeptides, glycolipids and/or sugars having a certain specific

Method of detecting pancreatic cancer

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BACKGROUND OF THE INVENTION 1. Technical Field The present invention relates to a method of detecting pancreatic cancer, and more particularly to a method of detecting pancreatic cancer in which pathological haptoglobin is used as a tumor marker. 2. Background Art Since pancreas is located deep in

Bifunctional glycoproteins having a modified carbohydrate complement and their use in tumor-selective therapy

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BACKGROUND OF THE INVENTION 1. Field of the Invention The invention relates to bifunctional glycoproteins having targeting protein and enzyme properties. More particularly, the invention relates to such proteins whose complements of carbohydrate residues have been modified in a manner that enhances

Process for screening for malignant tumors by determining the amount of GlcNAc transferase V activity

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BACKGROUND OF THE INVENTION This invention relates to a process for the determination of the malignant potential of a tumor, and diagnostic kits for carrying out the process. The process is suitable for the sensitive and specific determination of the malignant potential of a tumor. Neoplastic

Antibody-mediated anti-tumor activity induced by Reishi mushroom polysaccharides

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TECHNICAL FIELD OF THE INVENTION This invention relates to the field of cancer vaccines. In particular, the application relates to carbohydrate-based immunogenic compositions containing fucose-enriched polysaccharides isolated from a fucose-containing extract of Ganoderma lucidum. More particularly,

Therapeutic method using fucose-containing proteoglycan or acidic glycan

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to a class of proteoglycans having fucosylated acidic glycan side chains bound to a protein backbone which have been found to stimulate selectively proliferation of natural killer (NK) cells and/or .gamma..delta.T cells.

Fucose containing proteoglycan or acidic glycan and their pharmaceutical use

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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not Applicable BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to a class of proteoglycans having fucosylated acidic glycan side chains bound to a protein backbone which have been found to stimulate

Fucose containing proteoglycan or acidic glycan and their pharmaceutical use

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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not Applicable BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to a class of proteoglycans having fucosylated acidic glycan side chains bound to a protein backbone which have been found to stimulate

Disulfone reagents and methods of preparing and using same

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FIELD OF THE INVENTION The present invention relates generally to sulfone phosphonate compounds and their use in organic synthesis and, more particularly, to disulfone bis-phosphonates and their preparation and use as reagents in the synthesis of biologically relevant disulfones. BACKGROUND OF THE

Selectin binding glycopeptides

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FIELD OF THE INVENTION This invention relates generally to medicinal chemistry, and preferably to methods of synthesizing and identifying medically useful glyco-amino acids or glycopeptides which are characterized by their capacity to bind to one or more selectins CE-, L-, and

Monoclonal antibodies that bind to alpha-acid glycoprotein

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This invention relates to a monoclonal antibody and a method for the production thereof. More particularly, it relates to a monoclonal antibody specific for a .alpha..sub.1 -acid glycoprotein or specific for at least one antigenic determinant included in a sugar chain of the following formula which

Method for the analysis of N-glycans attached to immunoglobulin G from human blood plasma and its use

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CROSS REFERENCE TO RELATED APPLICATIONS This application is the U.S. National Phase Application of PCT/HR2014/000022, filed Jun. 11, 2014, which claims priority to Croatian Patent Application No. P20130568A, filed Jun. 20, 2013, the contents of such applications being incorporated by reference

Nutritional activation of telomerase in vitro and in vivo with increased safety

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BACKGROUND OF THE INVENTION Aging on the cellular level involves many paradoxes. On the one hand, many biochemical changes have been documented that suggest a variety of mechanisms of cellular aging. On the other hand, the simple expedient of increasing the expression of the enzyme telomerase is

Anti-CD19 antibody having ADCC and CDC functions and improved glycosylation profile

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FIELD OF THE INVENTION The present invention relates to an anti-CD19 antibody having a variant Fc region having some specific amino acid modifications relative to a wild-type Fc region which confer one or several useful effector functions. The present invention relates in particular to chimeric,

Anti-CD19 antibody having ADCC function with improved glycosylation profile

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FIELD OF THE INVENTION The present invention relates to an anti-CD19 antibody having a variant Fc region having some specific amino acid modifications relative to a wild-type Fc region which confer one or several useful effector functions. The present invention relates in particular to chimeric,
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