isopropanol/некроза

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Potentiation of the hepatotoxicity of N-nitrosodimethylamine by fasting, diabetes, acetone, and isopropanol.

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Previous studies indicate that pretreatment with acetone or isopropanol, fasting, and streptozotocin-induced diabetes enhance hepatic microsomal nitroso-dimethylamine (NDMA) demethylase in rats. This study demonstrates that these same treatments also potentiate the hepatotoxicity of NDMA as

Tumor necrosis factor activity in the circulation of horses given endotoxin.

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Serum and plasma from horses injected with endotoxin was examined for cytotoxic activity. Each of the cell lines, L929 and WEHI 164 clone 13, was sensitive to the cytotoxic effects of equine serum; however, a precipitation artifact caused by the use of isopropanol in the WEHI assay limited the use

The dysregulation of the monocyte/macrophage effector function induced by isopropanol is mediated by the defective activation of distinct members of the AP-1 family of transcription factors.

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Isopropanol is the second most common cause of short-chain alcohol acute intoxication. Nonethanolic short-chain alcohols mediate their immunomodulatory effect by interfering with nuclear factor of activated T cells (NFAT) activation with or without additional activator protein-1 (AP-1) involvement.

Crystallization and preliminary X-ray studies of mouse tumor necrosis factor.

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Well diffracting crystals of recombinant mouse tumor necrosis factor (mTNF) have been obtained. The sitting-drop vapor-diffusion method was used to grow crystals suitable for X-ray studies from solutions containing methoxypolyethylene glycol 2000 and isopropanol as precipitants. The crystals belong

First Report of 'Candidatus Phytoplasma aurantifolia' Associated With Severe Stunting and Necrosis on the Invasive Weed Pelargonium capitatum in Western Australia.

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Pelargonium capitatum (rose pelargonium) is a plant indigenous to southern Africa, originally brought to Western Australia for its ornamental qualities. It has since become naturalized in the Southwest Australian Floristic Region, recognized for its high level of species endemism, where it is a

[Endogenous toxemia in pancreatic necrosis of alcoholic etiology].

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Operation for pancreonecrosis was carried out in 197 patients, in 52 (26.4%) of them the disease was of alcoholic etiology. The disease was marked by severe clinical manifestations with the development of respiratory, hemodynamic, and peritoneal syndromes and their complications, and by psychic

Carrier free rapamycin loaded drug eluting stent: in vitro and in vivo evaluation.

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In the search for improving the performance of drug eluting stent (DES) various developments are in progress worldwide including use of carrier free DES, use of biodegradable polymers, biodegradable stents etc. In this work, carrier free-rapamycin (RM) coated DES has been prepared, and evaluated by

Methanol induces a discrete transcriptional dysregulation that leads to cytokine overproduction in activated lymphocytes.

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Methanol is an important cause of acute alcohol intoxication; it is ubiquitously present at home and in the workplace. Although the existing literature provides a reasonable insight into the immunological impact of ethanol and to a much lesser extent of isopropanol, much less data are available on

Effects of cadmium ions on the initial stage of translation and the cell death in mouse liver.

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OBJECTIVE To evaluate in vivo and in vitro effects of cadmium ions on the activities of mice liver tRNA(Leu)and leucyl-tRNA synthetase and on the type of liver cells death. METHODS White laboratory mice were intoxicated by intraperitoneal injection of cadmium chloride solution (1.6 mg cadmium ions/1

Decrease of carbon tetrachloride liver toxicity in rats given dipyridamole.

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The influence of Dipyridamole on acute hepatotoxicity has been studied in male SD-JCL rats doses with carbon tetrachloride. High single oral doses of Dipyridamole lowered the serum enzyme activity and reduced significantly the area % of hepatic necrosis and hydropic degeneration, but not of

Acute Pinesol toxicity in a domestic cat.

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The clinical, pathological and toxicological findings in a cat poisoned with Pinesol, a household cleaning agent, are reported. Clinically severe depression, with unresponsive pupils and extreme ataxia were observed prior to death. Pathologic changes consisted of severe acute centrilobular hepatic

Isolated liver damage in chemical workers.

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During a period of 18 months three workers were admitted to hospital with jaundice that had developed two to four months after beginning work at a chemical plant. Liver biopsies showed severe centrilobular, haemorrhagic liver cell necrosis. The pathological changes resolved within six to 18 months.

Characterization of the biochemical effects of naphthalene on the mouse respiratory system using NMR-based metabolomics.

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Naphthalene is a ubiquitous environmental pollutant to which humans are exposed. Previous studies have demonstrated that naphthalene causes bronchiolar epithelial necrosis in the mouse distal airway, after parenteral administration. In this study, metabolic variations in the bronchoalveolar lavage

Re-evaluation of the culture condition of polymorphonuclear cells for the study of apoptosis induction.

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The culture conditions of human peripheral blood polymorphonuclear leukocytes (PMN) in the study of apoptosis induction were re-evaluated. The changes in the relative viable cell number of PMNs after tumor necrosis factor (TNF) treatment were colorimetrically investigated using a cell counting kit.

First Report of Monosporascus cannonballus on Watermelon in Northern Mexico.

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In 2010 and 2011, diseased watermelon plants (Citrillus lanatus [Thunb.] Matsun and Nakai) had chlorotic and wilted leaves and vines prior to harvest in three out of four sampled commercial fields in the Municipality of Matamoros, State of Coahuila, in the north-central region of Mexico known as La

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