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phosphorylase/hypoxia
Врската е зачувана во таблата со исечоци
Страница 1 од 170 резултати
Thymidine phosphorylase and hypoxia-inducible factor 1-α expression in clinical stage II/III rectal cancer: association with response to neoadjuvant chemoradiation therapy and prognosis.
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The aim of this study was to determine whether pretreatment status of thymidine phosphorylase (TP), and hypoxia-inducible factor alpha (HIF-1α) could predict pathologic response to neoadjuvant chemoradiation therapy with oxaliplatin and capecitabine (XELOXART) and outcomes for clinical stage II/III
Features of glycogen phosphorylase from the body wall musculature of the lugworm Arenicola marina and the mode of activation during anoxia.
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The activities of glycogen phosphorylases a and b from the body wall musculature of the marine worm Arenicola marina (Annelida, Polychaeta) were determined after various periods of anoxia. Already under normoxic conditions one third of the total activity was produced from the a form. During anoxia
Influence of anoxia and dinitrophenol on Ca2+ efflux and phosphorylase a activity in rabbit colon smooth muscle.
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It was observed in earlier studies that when the phosphorylase alpha activity of rabbit colon smooth muscle was increased by anoxia or 2,4-dinitrophenol (DNP), the calcium content of the mitochondrial fraction decreased. Despite this, under basal conditions there was no significant increase in the
Activation of phosphorylase by anoxia and dinitrophenol in rabbit colon smooth muscle: relation to release of calcium from mitochondria.
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The effect of anoxia or 2,4-dinitrophenol (DNP) on the phosphorylase a activity and the calcium content in subcellular fractions from rabbit colon smooth muscle was studied. Anoxia for 15 min. as well as DNP (6.6 X 10(-5) M) for 5 min. increased the phosphorylase a activity. The calcium content in
Regulation of glycogen phosphorylase and PDH during exercise in human skeletal muscle during hypoxia.
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The present study examined the acute effects of hypoxia on the regulation of skeletal muscle metabolism at rest and during 15 min of submaximal exercise. Subjects exercised on two occasions for 15 min at 55% of their normoxic maximal oxygen uptake while breathing 11% O(2) (hypoxia) or room air
The effect of hypoxia on the activity of purine nucleoside phosphorylase in rats.
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The activity of purine nucleoside phosphorylase (PNP) in rat erythrocytes fractionated by centrifugation in microhematocrit capillaries was studied. After seven-day hypoxia (54 kPa) the PNP activity was increased by 67 +/- 4% (S.E.M.) in the lightest fraction of erythrocytes; on the fifth day after
Liver glycogen synthase and phosphorylase changes in vivo with hypoxia and anesthetics.
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Methods for obtaining and processing rat liver for determination of glycogen phosphorylase a and synthase I activity were studied. An extremely rapid and profound increase in phosphorylase was induced by hypoxia. The effect on synthase I was slower and less striking. Using alpha- and beta-adrenergic
Influence of anoxia and dinitrophenol on the phosphorylase a activity and the cyclic nucleotide content of smooth muscle.
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The effect of anoxia or 2,4-dinitrophenol (DNP) on the phosphorylase activity and the cyclic AMP and the cyclic GMP content was studied in smooth muscle preparations. When the aerobic conditions were changed to anaerobic in experiments on bovine mesenteric artery, there was a significant increase in
Hypoxia causes glycogenolysis without an increase in percent phosphorylase a in rat skeletal muscle.
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Stimulation of skeletal muscle to contract activates phosphorylase b-to-a conversion and glycogenolysis. Despite reversal of the increase in percentage of phosphorylase a after a few minutes, continued glycogen breakdown can occur during strenuous exercise. Hypoxia causes sustained glycogenolysis in
No relationship between thymidine phosphorylase (TP, PD-ECGF) expression and hypoxia in carcinoma of the cervix.
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The expression of hypoxia-regulated genes promotes an aggressive tumour phenotype and is associated with an adverse cancer treatment outcome. Thymidine phosphorylase (TP) levels increase under hypoxia, but the protein has not been studied in association with hypoxia in human tumours. An
Prevention of hypoxia-induced apoptosis by the angiogenic factor thymidine phosphorylase.
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The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase (PD-ECGF/TP) is expressed at higher levels in a wide variety of solid tumors compared to adjacent normal tissues. Patients with PD-ECGF/TP-positive colon and esophageal tumors have a poorer prognosis than
Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in Human breast cancer.
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Tumor-associated macrophages (TAMs) produce angiogenic factors and in breast cancer are associated with high vascular grade and poor survival. TAMs preferentially migrate to hypoxic areas within tumors and strongly express hypoxia-inducible factor (HIF)-2 alpha. This study examined whether HIF-2
Partially phosphorylated glycogen phosphorylase in the lugworm Arenicola marina, its regulatory function during hypoxia.
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Glycogen phosphorylase (GPase) from the body wall of the lugworm Arenicola marina (Annelida, Polychaeta) probably exists as a phospho-dephospho hybrid (GPase ab). The hybrid was identified by phosphorylation of purified lugworm GPase b (unphosphorylated form) with rabbit muscle GPase kinase and
Phosphorylase alpha and labile metabolites during anoxia: correlation to membrane fluxes of K+ and Ca2+.
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The objective of the present study was to explore mechanisms responsible for activation of ion conductances in the initial phases of brain ischemia, particularly for the early release of K+ that precedes massive cell depolarization, and rapid downhill fluxes of K+, Na+, Cl-, and Ca2+. As it has been
Acetylcholine modulation of phosphorylase and contractility in rat hearts exposed to anoxia or isoproterenol.
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Најкомплетната база на податоци за лековити билки поддржана од науката
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