Страница 1 од 27 резултати
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the fields of molecular genetics, cancer biology, cancer prevention, and cancer chemotherapy. More specifically, the present invention relates to the c-DNA cloning and nucleotide sequencing of a novel
FIELD OF THE INVENTION
This invention pertains to certain novel tocopherol ester derivatives and intermediate compounds utilized in the preparation of the derivatives. More specifically, this invention pertains to .alpha.-tocopherol ester compounds that exhibit antiproliferative and growth
FIELD OF INVENTION
The present invention is generally related to the discovery of the therapeutic benefit of administering .gamma.-tocopherol and .gamma.-tocopherol derivatives. More specifically, the use of .gamma.-tocopherol and racemic LLU-.alpha., (S)-LLU-.alpha., or other .gamma.-tocopherol
FIELD OF INVENTION
The present invention is generally related to the discovery of the therapeutic benefit of administering .gamma.-tocopherol and .gamma.-tocopherol derivatives. More specifically, the use of .gamma.-tocopherol and racemic LLU-.alpha., (S)-LLU-.alpha., or other .gamma.-tocopherol
II. FIELD OF INVENTION
The present invention is generally related to the discovery of the therapeutic benefit of administering .gamma.-tocopherol and .gamma.-tocopherol derivatives. More specifically, the use of .gamma.-tocopherol and racemic LLU-.alpha., (S)-LLU-.alpha., or other .gamma.-tocopherol
II. FIELD OF INVENTION
The present invention is generally related to the discovery of the therapeutic benefit of administering .gamma.-tocopherol and .gamma.-tocopherol derivatives. More specifically, the use of .gamma.-tocopherol and racemic LLU-.alpha., (S)-LLU-.alpha., or other .gamma.-tocopherol
FIELD OF INVENTION
The present invention is generally related to the discovery of the therapeutic benefit of administering .gamma.-tocopherol and .gamma.-tocopherol derivatives. More specifically, the use of .gamma.-tocopherol and racemic LLU-.alpha., (S)-LLU-.alpha., or other .gamma.-tocopherol
1. INTRODUCTION
The present application relates to methods of treating or preventing proliferative disease, particularly cancer, by administering to a subject a composition comprising lycopene and alpha-tocopherol.
2. BACKGROUND OF THE INVENTION
Lycopene, a natural red carotenoid found in nature in
FIELD OF THE INVENTION
The invention relates to a substantially non-toxic water dispersible therapeutic formulation including a substantially water insoluble therapeutic agent selected from the group consisting of carotenoid compositions and tocopherols that can be administered to animals, including
FIELD OF THE INVENTION
This invention relates to methods for administration of taxane/tocopherol formulations for the treatment of cancer.
BACKGROUND OF THE INVENTION
Paclitaxel is one of the most potent anticancer agents for the treatment of several cancers, including breast, ovarian, and lung
This application is a 371 of PCT/JP95/01975 filed Sep. 28, 1995.
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a novel tricyclic, condensed heterocyclic compound. The novel tricyclic, condensed heterocyclic compound in accordance with the present invention is a useful substance
FIELD OF THE INVENTION
The present invention relates to an improved liposome/anthraquinone therapeutic composition having reduced lipid oxidation and free-radical damage, and to methods for preparing and using the composition.
REFERENCES
Aubel-Sadron, G., et al, Biochemie, 66:333 (1984).
Augustin,
FIELD OF THE INVENTION
The present invention relates to an improved liposome/anthraquinone therapeutic composition having reduced lipid oxidation and free-radical damage, and to methods for preparing and using the composition.
REFERENCES
Aubel-Sadron, G., et al, Biochemie, 66: 333 (1984).
Augustin,
1. FIELD OF THE INVENTION
The present invention relates to an improved liposome/anthraquinone therapeutic composition having reduced lipid oxidation and free-radical damage, and to methods for preparing and using the composition.
2. REFERENCES
Aubel-Sadron, G., et al, Biochemie, 66:333
FIELD OF THE INVENTION
The present invention relates to compositions comprising a combination of at least one source of .delta.-tocols (tocotrienol and/or tocopherol), with an antioxidant source comprising polyphenolic compounds. Due to synergistic effects, such compositions are useful in treating