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11 резултати
Development of spontaneous, age-related nonconvulsive seizure electrocortical activity and radial-maze learning after exposure to m-xylene in rats.
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It has been hypothesized that exposure to neurotoxins may result in accelerated ageing of the central nervous system (CNS). The present study investigated the effects of a 3-month (6 hr daily, 5 days/week) inhalation exposure of rats to m-xylene, at concentrations of 100 and 1000 ppm, on the
Can xylene (xylol) provoke convulsive seizures?
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Neutrotropic effects and blood levels of solvents at combined exposures: binary mixtures of toluene, o-xylene and acetone in rats and mice.
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Male rats and female mice were exposed to vapours of toluene, o-xylene and acetone in basic or double concentrations or to binary combinations of basic concentrations, for 4 and 2 hours, respectively. Basic air concentrations were for rats and mice (in ppm): toluene 270 and 380, o-xylene 230 and
Intravenous thiodan (30% endosulfan in xylene).
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OBJECTIVE
We report the first case of intravenous self-poisoning with Thiodan (30% endosulfan in xylene).
METHODS
A 28-year-old woman with a past history of epilepsy presented with refractory grand mal seizures after injecting 1 mL of Thiodan intravenously. She developed liver dysfunction, proximal
Acute ingestion poisoning with insecticide formulations containing the pyrethroid permethrin, xylene, and surfactant: a review of 48 cases.
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BACKGROUND
Forty-eight patients poisoned with insecticide formulations containing permethrin (a Type I pyrethroid insecticide), xylene, and surfactants are reported here. These patients were diagnosed and treated in the Chang Gung Memorial Hospital in Taiwan from January 1987 to June 1999. Ten
[Pharmacological Effects of Different Prepared Typhonii Rhizoma].
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To evaluate the different actions of crude and prepared Typhonii Rhizoma through pharmacological and statistical methods.
Spontaneous activity test, sleep test, and seizure induced by dimefline in mice were used to examine the sedative and anticonvulsant effects of different prepared products of
Structure-activity relationship for the anticonvulsant effects of organic solvents.
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Several organic solvents have anticonvulsant or convulsant actions depending on the dose and exposure time. To study if there is a structure-activity relationship for organic solvents as anticonvulsant agents we subjected independent groups of mice to a single 30-min exposure session to inhale
Anticonvulsant and antipunishment effects of toluene.
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Toluene can have striking acute behavioral effects and is subject to abuse by inhalation. To determine if its actions resemble those of drugs used in the treatment of anxiety ("anxiolytics"), two sets of experiments were undertaken. Inasmuch as prevention of pentylenetetrazol-induced convulsions is
Anesthetic and convulsant properties of aromatic compounds and cycloalkanes: implications for mechanisms of narcosis.
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We examined the anesthetic and convulsant properties of 16 unfluorinated to completely fluorinated aromatic compounds, having six to nine carbon atoms (e.g., benzene to 1,3,5-tris(trifluoromethyl)benzene), and four cycloalkanes (cyclopentane to cyclooctane). Benzene, fluorobenzene, toluene,
Improved selective, simple, and contrast staining of acidophilic neurons with vanadium acid fuchsin.
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Acidophilia is one of the hallmarks of acute neuronal damage and death in brain ischemia, excitotoxic and traumatic lesions and epileptic seizures. We here describe a novel and simple method for visualizing acidophilic neurons on paraffin sections, using vanadium acid fuchsin (VAF) staining and
Amygdala kindling in immature rats: proconvulsant effect of the organophosphate insecticide-chlorpyrifos.
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Administration of the organophosphate insecticide, chlorpyrifos to immature rats exerted a proconvulsant effect on seizures induced by kindling. Chlorpyrifos was administered to 16 or 17 day old rats in a dose range of 0.3 to 10 mg/kg, subcutaneously. Amygdala kindling was performed by stimulating
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