5 үр дүн
CROSS-REFERENCE TO RELATES APPLICATIONS
This application is filed under the provision of 35 U.S.C. .sctn.371 and claims the priority of International Patent Application No. PCT/ES03/000635 filed Dec. 16, 2003, which in turn claims priority of Spanish Patent Application No. P200202911 filed Dec. 18,
The invention relates to improvement of the transport properties of an albumin produced on an industrial scale, for example by the Cohn Process or by recombinant methods, with substances that saturate the binding sites on the albumin and therefore impair the binding and transport properties of the
REFERENCE TO A "SEQUENCE LISTING," A TABLE, OR A COMPUTER PROGRAM LISTING APPENDIX SUBMITTED AS AN ASCII TEXT FILE
The Sequence Listing written in file 92494-867804_ST25.TXT, created on Mar. 24, 2013, 114,846 bytes, machine format IBM-PC, MS-Windows operating system, is hereby incorporated by
SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Jul. 3, 2012, is named 1320USPR.txt and is 450,377 bytes in size.
BACKGROUND OF THE
1. INTRODUCTION
The present invention relates to the propagation of human hepatocytes in the livers of non-human animals that have been tolerized to the human cells. Such animals provide an in vivo model system of the human liver that may be used in toxicology assays and in the study of human liver