14 үр дүн
BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention relates generally to the fields of biology and medicine. More particularly, it concerns compounds, compositions and methods for the treatment and prevention of diseases such as those associated with oxidative stress and
FIELD OF THE INVENTION
This invention relates generally to the field of medicinal chemistry. More specifically, it relates to derivatives of triterpenoid acids, preferably derivatives of glycyrrhetinic acid, that have dual pharmacophoric properties, formulations containing such and their use to
FIELD OF THE INVENTION
This invention relates generally to the field of medicinal chemistry. More specifically, it relates to derivatives of triterpenoid acids, preferably derivatives of glycyrrhetinic acid, that have dual pharmacophoric properties, formulations containing such and their use to
FIELD OF THE INVENTION
This invention relates generally to the field of medicinal chemistry. More specifically, it relates to derivatives of triterpenoid acids, preferably derivatives of glycyrrhetinic acid, that have dual pharmacophoric properties, formulations containing such and their use to
FIELD OF THE INVENTION
This invention relates generally to the field of medicinal chemistry. More specifically, it relates to derivatives of triterpenoid acids, preferably derivatives of glycyrrhetinic acid, that have dual pharmacophoric properties, formulations containing such and their use to
BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention relates generally to the fields of biology and medicine. More particularly, it concerns compounds, compositions and methods for the treatment and prevention of diseases such as those associated with oxidative stress and
FIELD OF THE INVENTION
This invention relates generally to the field of chemical compounds, and to methods of treatment and detection. More specifically, this invention relates to derivatives of triterpenoid acids, formulations containing such and their use in treating patients by binding to and/or
FIELD OF THE INVENTION
This invention relates generally to the field of chemical compounds, and to methods of treatment and detection. More specifically, this invention relates to derivatives of triterpenoid acids, formulations containing such and their use in treating patients by binding to and/or
BACKGROUND OF THE INVENTION
PGE2 belongs to the family of prostaglandins (PGs), which are a group of biologically active compounds found in virtually all tissues and organs. They are synthesized from the metabolism of a membrane lipid, arachidonic acid, by cyclooxygenases to the intermediate PGH2,
Provided are certain chemical entities, pharmaceutical compositions and methods for the treatment of inflammatory, neurodegenerative, neoplastic and autoimmune diseases.
Numerous molecular and cellular events are associated with inflammatory disease processes. Such events may be defensive in the
BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention provides triterpenoid derivatives, as well as processes for the preparation of such derivatives. The invention also provides methods for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease,
BACKGROUND OF THE INVENTION
Triterpenoids are biosynthesized in plants by the cyclization of squalene. Although candidates for medicinal use, these naturally occurring molecules display relatively weak biological activity. Accordingly, chemists have sought to synthesize analogues of enhanced potency
BACKGROUND OF THE INVENTION
Triterpenoids are biosynthesized in plants by the cyclization of squalene. Although candidates for medicinal use, these naturally occurring molecules display relatively weak biological activity. Accordingly, chemists have sought to synthesize analogues of enhanced potency
BACKGROUND OF THE INVENTION
Triterpenoids are biosynthesized in plants by the cyclization of squalene. Although candidates for medicinal use, these naturally occurring molecules display relatively weak biological activity. Accordingly, chemists have sought to synthesize analogues of enhanced potency