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Efficacy of AloeVera Gel Gum Massaging and Adjunct to Scaling and Root Planing in Chronic Periodontitis Patients

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Government College of Dentistry, Indore

Sleutelwoorden

Abstract

Periodontal disease is a multifactorial disease caused by mainly bacterial, genetic, immunologically, and environmental factors. Chronic periodontitis, one of the widely prevalent forms of periodontal disease, is characterized by loss of attachment apparatus of the tooth; it can lead to tooth loss. Many non surgical and surgical approaches have been adapted time and again to prevent, intercept, and to treat the various forms of chronic periodontitis. But, these treatment modalities are not approachable by all individuals, because of the various factors such as: low socioeconomic status, illiteracy, high cost of the treatment, no availability of easy and uncomplicated treatment nearby etc. Considering these factors, we are still in need of preventive, practical, and affordable treatment options specially for the population of underdeveloped and developing countries.

Omschrijving

Periodontal disease is universally prevalent. It is a multifactorial disease caused by mainly bacterial, genetic, immunologically, and environmental factors. Chronic periodontitis, one of the widely prevalent forms of periodontal disease, is characterized by loss of attachment apparatus of the tooth; it can lead to tooth loss. Many non surgical and surgical approaches have been adapted time and again to prevent, intercept, and to treat the various forms of chronic periodontitis. But, these treatment modalities are not approachable by all individuals, because of the various factors such as: low socioeconomic status, illiteracy, high cost of the treatment, no availability of easy and uncomplicated treatment nearby etc. Considering these factors, we are still in need of preventive, practical, and affordable treatment options specially for the population of underdeveloped and developing countries.

The use of medicinal plants in the prevention and treatment of the various diseases need not to be over emphasized, as their uses had been advocated in treatises: Sushruta Samhita and Charka Samhita, a long back. Now, it is a demand of time to reread and get the valuable informations for the use of Medical and Dental sciences. These information will be very valuable specially, in context of under developed and developing countries.

One of the herbs -'Aloe Vera' is a very important medicinal plant. The name 'Aloe Vera' is derived from the Arabic Word "Alloeh" meaning "Shining bitter substance," while "Vera" in Latin means "true". Over the years, this plant has been known by a number of names such as 'Wand of heaven', 'Heaven's blessing, and 'the Silent healer'. Plant Aloe Vera is known to us since the ancient time which has stiff grey green lance shaped leave. These leaves hold clear gel in a central mucilaginous pulp. This polysaccharide gel is responsible for beneficial properties of Aloe Vera.1 Aloe Vera gel polysaccharide acemannan has been found to be effective in activating macrophages and resulted in improved wound healing in a rat model. A novel anti-inflammatory compound c -glucosyl chromones has been extracted from the Aloe vera gel. Antibacterial property against gram positive and gram negative bacteria has also been documented.2 Some studies have also shown its antifungal, antiviral, bactericidal, and virucidal activities. A number of investigations have attempted to relate the chemical constituents in the gel to specific biological effects, such as wound healing effect,3 skin hydration effect,4 anti ageing effec,5 anti-inflammatory effect,6 anti bacterial property,2 anti fungal property7, anti viral effect,8 immunomodulating effect,9 anti tumour effect,10 and laxative effect.11 In Dentistry, clinical applications of Aloe Vera have been seen in the treatment of Apthous ulcers, Oral lichen Planus, Alveolar osteitis, and denture adhesive.12 Moreover, several studies have shown the efficacy of Aloe Vera in treating Gingivitis.13 In another study the effect of tooth paste containing high concentration of Aloe Vera, has been observed on the reduction of plaque and gingivitis.14 In underdeveloped and developed countries the application of simple and cost effective approaches are required. Therefore, this study has been planned to evaluate the clinical efficacy of Aloe Vera in moderate to severe form of Generalized Chronic Periodontitis in Indian patients.

Very few studies, which can be counted on fingers, have been conducted worldwide. Hence, this study is being taken to evaluate the Efficacy of Aloe Vera Gel in Gingival Massaging and as an Adjunct to Scaling and Root

Datums

Laatst geverifieerd: 02/28/2017
Eerste ingediend: 03/13/2017
Geschatte inschrijving ingediend: 03/16/2017
Eerst geplaatst: 03/19/2017
Laatste update ingediend: 03/16/2017
Laatste update geplaatst: 03/19/2017
Werkelijke startdatum van het onderzoek: 12/31/2015
Geschatte primaire voltooiingsdatum: 02/28/2017
Geschatte voltooiingsdatum van het onderzoek: 02/28/2017

Conditie of ziekte

CHRONIC PERIODONTITIS

Interventie / behandeling

Procedure: Tooth Brushing

Procedure: aloe vera Massaging

Procedure: SRP with aloe vera massaging

Fase

-

Armgroepen

ArmInterventie / behandeling
Active Comparator: Tooth Brushing
Tooth brushing with dentifrice and standardized tooth brush
Experimental: Aloe vera massaging
Tooth brushing with dentifrice and standardized tooth brush followed by massaging with aloe vera gel
Experimental: SRP with aloe vera massaging
Scaling and root planning was done with ultrasonic scalar. It was followed by aloe vera massaging on half arch for 3 minutes daily
Procedure: SRP with aloe vera massaging
on one side of the arch only Scaling and Root Planing(SRP) to be done, while on the other side, after the Scaling and Root Planing massaging with aloe vera ge; shall be carried out by the patients/subjects

Geschiktheidscriteria

Leeftijden die in aanmerking komen voor studie 35 Years Naar 35 Years
Geslachten die in aanmerking komen voor studieFemale
Accepteert gezonde vrijwilligersJa
Criteria

Inclusion Criteria:

- Cases with moderate to severe form of Generalised Chronic Periodontitis patients of any sex.

- Patients in the age group of 35-65 years, who abide by approved protocol guidelines, and are ready to give written informed consent.

Exclusion Criteria:

- Any known systemic disease which has effects on periodontium such as diabetes etc.

- Patients on anti-inflammatory, antibiotics and perioceutics, since 3 months.

- Patients who have known allergy to material used for the study.

- Pregnant and lactating mothers.

- Patients had undergone any kind of non-surgical and/or surgical periodontal therapy earlier, in past 6 months.

- Tobacco users.

Resultaat

Primaire uitkomstmaten

1. Plaque Index (Turesky modification of Quigley Hein Index, 1970) [baseline]

Secundaire uitkomstmaten

1. Plaque Index (Turesky modification of Quigley Hein Index, 1970) [1 week]

2. Plaque Index (Turesky modification of Quigley Hein Index, 1970) [2 week]

3. Plaque Index (Turesky modification of Quigley Hein Index, 1970) [4 week]

4. Plaque Index (Turesky modification of Quigley Hein Index, 1970) [6 week]

5. Gingival Index (Loe H and Silness J 1963) [baseline]

6. Gingival Index (Loe H and Silness J 1963) [1 week]

7. Gingival Index (Loe H and Silness J 1963) [2 week]

8. Gingival Index (Loe H and Silness J 1963) [4 week]

9. Gingival Index (Loe H and Silness J 1963) [6 week]

10. Russell's Periodontal Index (Rusell's A.L, 1956) [baseline]

11. Russell's Periodontal Index (Rusell's A.L, 1956) [1 week]

12. Russell's Periodontal Index (Rusell's A.L, 1956) [2 week]

13. Russell's Periodontal Index (Rusell's A.L, 1956) [4 week]

14. Russell's Periodontal Index (Rusell's A.L, 1956) [6 week]

15. Periodontal Probing Depth [baseline]

16. Periodontal Probing Depth [1 week]

17. Periodontal Probing Depth [2 week]

18. Periodontal Probing Depth [4 week]

19. Periodontal Probing Depth [6 week]

20. Clinical Attachment Levels [baseline]

21. Clinical Attachment Levels [1 week]

22. Clinical Attachment Levels [2 week]

23. Clinical Attachment Levels [4 week]

24. Clinical Attachment Levels [6 week]

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