[Analysis of histopathologic parameters and symptomatology in patients with chronic rhinosinusitis with nasal polyps after endoscopic sinus surgery].
Sleutelwoorden
Abstract
OBJECTIVE
To estimate the predictable value of histopathologic parameters in chronic rhinosinusitis with nasal polyps (CRSwNP) after endoscopic sinus surgery(ESS).
METHODS
Symptomatology was rated in 53 patients 12 to 24 months after ESS. Specimens taken during the surgical procedure were examined and scored for eosinophils, goblet cells, lymphocytes, subepithelial thickening, subepithelial edema and submucous gland formation. The correlation between histopathologic parameters and postoperative symptoms was then evaluated.
RESULTS
The most common symptome after ESS were nasal obsruction, nasal secretion, discharge and sneezing. The correlation between goblet cells and sneezing, discharge, submucous gland formation and headache, subepithelial edema and postnasal secretion was significant (P < 0.05).
CONCLUSIONS
Certain histopathologic parameters in CRSwNP are predictive of favorable response to ESS.
