Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 2003-May
[Effect of Sorbaria Sorbifolia extract on anti-oxidative activities in rats with precancerosis induced by diethylnitrosamine].
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Sleutelwoorden
Abstract
OBJECTIVE
To study the effect of Sorbaria Sorbifolia extract on anti-oxidative activities in rats with precancerosis induced by diethylnitrosamine.
METHODS
Sorbaria sorbifolia was perfused into stomach of rats with DEN-induced precancerosis, then the biochemical indexes were investigated. The activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-PX), and the concentrations of malondialdehyde (MDA), glutathione (GSH) were investigated by colorimetric method.
RESULTS
Sorbaria sorbifolia extract increased SOD, GSH-PX and decreased MDA, GSH levels in serum and liver homogenate.
CONCLUSIONS
Sorbaria Sorbifolia extract significantly increased anti-oxidative activities in rats with precancerosis induced by diethylnitrosamine.
