Biochemical medicine 1983-Apr
In vitro absorption of [14C]leucine during inflammation and the effect of antiinflammatory drugs in the jejunum of rats.
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Abstract
1. Inflammation was induced in the hindlegs of rats by formalin injection and the in vitro absorption of [14C]leucine was studied. 2. Treatment of rats with formalin caused a reduction in the in vitro absorption of leucine from the mucosa of jejunum. 3. Oral administration of oxyphenbutazone or a herbal anti-inflammatory drug (Withania somnifera) prior to formalin injection resulted in no alteration in the jejunal absorption of [14C]leucine.