[The baseline value of gastric secretion indices for the reactivity of the stomach secretory apparatus in response to disturbing factors].

The stomach reactivity to the impact of a number of disturbing factors depending on the baseline gastric secretion indices was examined. Fistula dogs, the secretion of which was carbacholine stimulated (6 mg/kg), were subjected to experiments. The volume of gastric secretion, proteolytic activity, activity of hydrogen ions and volume of secreted mucus were determined. Animals were divided into two groups depending on these indices during control experiments: a group with a low secretion level and a group with a high secretion level. Immobilization stress, mineral water from the lake of Shira and proline-containing peptide Gli-Pro were the disturbing factors.

RESULTS

If the level of secretion parameters is low, it decreases after the impact and vice versa. The impact of the disturbing factors caused no changes at their medium volumes. This self-regulation rule became most apparent during the complex reflex stage of gastric juice secretion.