Clinica Chimica Acta 1978-Mar
The effect of experimental uremia on potassium-activated phosphatase from erythrocyte and cardiac membranes.
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Abstract
Unilateral nephrectomy and partial resection of the contralateral kidney in rats causes uremia that lasts for several weeks and influenced overall (Na+, K+)-ATPase activity as well as p-nitrophenyl phosphatase (p-NPPase) in the plasma membranes of erythrocytes and heart. Both enzymatic activities are inhibited to a similar extent in the uremic animals, regardless of whether the membranes were investigated one or four weeks after surgical treatment.