Indian Pediatrics 2012-Jan
Venovenous hemodiafiltration and hypothermia for treatment of cerebral edema associated with hyperammonemia.
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Abstract
We report a 50 hour old newborn with inborn urea cycle disorder and hyperammonia of 2320 umol/L. The pharmacological treatment of the first metabolic crisis was combined with venovenous hemodiafiltration and therapeutic hypothermia to rescue the patient from a life-threatening cerebral edema.