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Bladzijde 1 van 67 resultaten
Diagnostic method and system for detecting early age macular degeneration, maculopathies and cystoid macular edema post cataract surgery
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FIELD OF THE INVENTION
This invention relates to a method and system for using a calibrated retinoscope and parallel light technique to estimate the reflection of melanin particles in the retina to detect macular degeneration prior to physical symptoms.
BACKGROUND OF THE INVENTION
In the Western
Diagnostic method and system for detecting early age-related macular degeneration, maculopathies and cystoid macular edema post cataract surgery
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FIELD OF THE INVENTION
This invention relates to a method and system for using a calibrated retinoscope and parallel light technique to estimate the reflection of melanin particles in the retina to detect macular degeneration prior to physical symptoms.
BACKGROUND OF THE INVENTION
In the Western
Treatment of macular edema
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BACKGROUND OF THE INVENTION
Macular edema is swelling within the retina within the critically important central visual zone at the posterior pole of the eye. An accumulation of fluid within the retina tends to distract the neural elements from one another and from their local blood supply, creating
Compositions and methods for treating macular edema
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FIELD OF THE INVENTION
The present disclosure generally relates to compositions and methods for the prevention, stabilization and/or treatment of macular edema, in particular that results from central retinal vein occlusion (CRVO), branch retinal vein occlusion (BRVO), age related macular
Norrin regulation of cellular production of junction proteins and use to treat retinal vasculature edema
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FIELD OF THE INVENTION
The present invention is directed generally to methods of regulating VE-cadherin and claudin gene expression in retinal tissue by applying to such tissue norrin protein; and in particular, to produce additional cellular production of VE-cadherin and claudin-5 in retinal
Norrin regulation of cellular production of junction proteins and use to treat retinal vasculature edema
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FIELD OF THE INVENTION
The present invention is directed generally to methods of regulating VE-cadherin and claudin gene expression in retinal tissue by applying to such tissue norrin protein; and in particular, to produce additional cellular production of VE-cadherin and claudin-5 in retinal
Methods and compositions for treatment of macular and retinal disease
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FIELD OF THE INVENTION
The present invention relates to methods and compositions for treatment and prevention of disease, and in particular embodiments, disorders of the eye. In an embodiment, the present invention describes linking therapeutic compounds to xanthophyll carotenoids to enhance
Quinoline derivatives and their use as tyrosine kinase inhibitors
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FIELD OF THE INVENTION
The present invention relates to quinoline derivatives and to the use thereof in therapy. More particularly, the present invention relates to quinoline derivatives for the treatment of cancer, diabetic retinopathy, age-related macular degeneration, inflammation, stroke,
Quinoline derivatives and their use as tyrosine kinase inhibitors
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FIELD OF THE INVENTION
The present invention relates to quinoline derivatives and to the use thereof in therapy. More particularly, the present invention relates to quinoline derivatives for the treatment of cancer, diabetic retinopathy, age-related macular degeneration, inflammation, stroke,
Glucocorticoids attached to nitrate esters via an aromatic linker in position 21 and their use in ophthalmology
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The invention relates to nitrooxy derivatives of steroids, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating ocular diseases, in particular diabetic macular edema, diabetic retinopathy, macular
Glucocorticoids attached to nitrate esters via an aromatic linker in position 21 and their use in ophthalmology
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The invention relates to nitrooxy derivatives of steroids, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating ocular diseases, in particular diabetic macular edema, diabetic retinopathy, macular
Therapeutic treatment for VEGF related ocular diseases
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention is broadly directed to a method for inhibiting endothelial cell growth and capillary permeability associated with vascular endothelial growth factor (VEGF), e.g., the increased cell growth and permeability induced by VEGF
Tyrosine kinase inhibitors
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BACKGROUND OF THE INVENTION
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,
Polymorphs with tyrosine kinase activity
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BACKGROUND OF THE INVENTION
The present invention relates to active polymorphs of 4-[2-(5-cyano-thiazol-2-ylamino)-pyridin-4-ylmethyl]-piperazine-1-carboxyl ic acid methylamide, which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these polymorphs,
Substituted pyrazolo[1,5-A]pyrimidines as tyrosine kinase inhibitors
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BACKGROUND OF THE INVENTION
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,
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