calotropis/antimycoticum

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Osmotin from Calotropis procera latex: new insights into structure and antifungal properties.

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This study aimed at investigating the structural properties and mechanisms of the antifungal action of CpOsm, a purified osmotin from Calotropis procera latex. Fluorescence and CD assays revealed that the CpOsm structure is highly stable, regardless of pH levels. Accordingly, CpOsm inhibited the

New constitutive latex osmotin-like proteins lacking antifungal activity.

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Proteins that share similar primary sequences to the protein originally described in salt-stressed tobacco cells have been named osmotins. So far, only two osmotin-like proteins were purified and characterized of latex fluids. Osmotin from Carica papaya latex is an inducible protein lacking

Preliminary Anti-Fungal Activity of the Aqueous Bark Extract of Calotropis procera (ASCLEPIADACEAE).

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BACKGROUND Calotropis procera is a species of flowering plant which belongs to the Asclepiadaceous family. Its other names are Apple of Sodom, Giant Milkweed and Swallow-wort. It's native to Africa and Asian countries where they exist as a spreading shrub or small tree with height of about 4m. They.

Effect of plant extracts and systemic fungicide on the pineapple fruit-rotting fungus, Ceratocystis paradoxa.

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Antifungal activities of extracts of sixteen plants were tested against Ceratocystis paradoxa which causes soft rot of pineapples. Xanthium strumarium was the most effective followed by Allium sativum. The effectiveness of various extracts against C. paradoxa was in the decreasing order of Meriandra

Identification, characterization, and antifungal activity of cysteine peptidases from Calotropis procera latex.

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Cysteine peptidases (EC 3.4.22) are the most abundant enzymes in latex fluids. However, their physiological functions are still poorly understood, mainly related to defense against phytopathogens. The present study reports the cDNA cloning and sequencing of five undescribed cysteine peptidases from

Ethnoveterinary Therapeutic Practices and Conservation Status of the Medicinal Flora of Chamla Valley, Khyber Pakhtunkhwa, Pakistan.

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Domestic animals play a very important role in the human civilization. Besides human being, plants are used as medicines for many domestic animals. The therapeutic practices are very common among the tribes of Chamla, rich in ethnoveterinary medicinal plants. Due to poor availability of modern

Crystal structure of an antifungal osmotin-like protein from Calotropis procera and its effects on Fusarium solani spores, as revealed by atomic force microscopy: Insights into the mechanism of action.

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CpOsm is an antifungal osmotin/thaumatin-like protein purified from the latex of Calotropis procera. The protein is relatively thermostable and retains its antifungal activity over a wide pH range; therefore, it may be useful in the development of new antifungal drugs or transgenic crops with

CD146 T cells in lung cancer: its function, detection, and clinical implications as a biomarker and therapeutic target.

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CD146 alternatively called melanoma cell adhesion molecule (MCAM), is a biomarker and therapeutic target of clinical significance. It is found on different cells including the endothelial cells and lymphocytes which participate in heterotypic and homotypic ligand-receptor. This review concentrated

Crystallization and X-ray diffraction analysis of an antifungal laticifer protein.

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An osmotin (CpOsm) from the latex of Calotropis procera has been crystallized in both tetragonal and trigonal forms suitable for structure determination. Crystallographic studies of CpOsm are of great interest because limited information is available concerning the structure of latex proteins and

Antimycoplasmal activity of some plant species from northern Nigeria compared to the currently used therapeutic agent.

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BACKGROUND Mycoplasma spp. are obligate parasites of humans and animals. But due to the special requirements needed to culture Mycoplasma in the laboratory, little or no research has been done to evaluate the efficacy of medicinal plants on the organism. OBJECTIVE To screen medicinal plants

Anti-inflammatory latex proteins of the medicinal plant Calotropis procera: a promising alternative for oral mucositis treatment

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Objective and design: Oral mucositis (OM) is an intense inflammatory reaction progressing to tissue damage and ulceration. The medicinal uses of Calotropis procera are supported by anti-inflammatory capacity. PII-IAA, a highly homogenous cocktail of laticifer

The Metabolomic study of Calotropis procera Ait. from Burkina Faso, based on chemical functional groups profiling using FTIR

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Background C. procera is an important wild medicinal plant used in different area of Burkina Faso for the neuropsychiatric disorders treatment. It was reported to possess many pharmacological properties because of its phytochemical diversity. This study was carried out to identify possible specific

Chemometric profile & antimicrobial activities of leaf extract of Calotropis procera and Calotropis gigantea.

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Calotropis procera and Calotropis gigantea are medicinal plant having therapeutic value. The leaf extracts of C. procera have been investigated, its pharmacological actions in detail and leaf extracts of C. gigantea were not studied till date. The objective of present work was to find the bioactive

Protection afforded by methanol extract of Calotropis procera latex in experimental model of colitis is mediated through inhibition of oxidative stress and pro-inflammatory signaling.

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Calotropis procera, a latex producing plant is known to possess medicinal properties including its beneficial effect in gastrointestinal disorders. The anti-inflammatory effect of its latex in various experimental models is noteworthy and in light of this the present study was carried out with an

In Vivo Efficacy of Latex from Calotropis procera in Ameliorating Fever-Biochemical Characteristics and Plausible Mechanism.

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Calotropis procera latex fractions possessing anti-inflammatory property were characterized for their biochemical properties, compared for their efficacy in ameliorating fever in rats and their mechanism of action was elucidated. Aqueous fraction and methanol extract (AqDL and MeDL) were derived

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