Liposomal Bupivacaine (1.3%) solution (20 mL dose). This solution has demonstrated increased efficacy in prolonged analgesia following injection. This solution will be injected as an ultrasound-guided subpectoral interfacial plane block.

Normal saline (0.9%) will be used as the control solution for patients not receiving the liposomal bupivacaine solution. Injection procedure of this solution will be identical to that of the liposomal bupivacaine solution.

Cardiovascular Surgery

Pain, Postoperative

Block

Sternal Block during Coronary Artery Bypass Graft Surgery and/or surgical aortic valve replacement through mini- or full sternotomy

Liposomal bupivacaine

Normal Saline Flush, 0.9% Injectable Solution_#1

Baylor Scott & White Heart Hospital - Plano

Sternal Block With Liposomal Bupivacaine vs. Saline Prior to Incision in Cardiac Surgery

Regional Blockade of the Sternum With Liposomal Bupivacaine Prior to Incision Decreases Opioid Use in Patients Undergoing Cardiac Surgery (Sternal Block)

The amount of opioid medications used will be recorded during the routine postoperative course.

At this point, we do not plan to shared IPD but will share cumulative results in an abstract and manuscript.

Baylor Research Institute

The surgeon, coordinator and anesthesiologist on the case are blinded to the block drug. A 2nd (unblinded) anesthesiologist performs the block on the patient.

Pancreatitis

glyceryl nitrate

Department of Medical and Surgical Gastroenterology, KAS Glostrup

Dept. of Medical Gastroenterology F, KAS Gentofte

Gastroenheden, Hvidovre Hospital

Rigshospitalet

Køge County Hospital

Dept of Medical Gastroenterology S, Odense Universitetshospital

Serv Gastroenterologie Hopital Sainte Marguerite

North Hospital

Div of Gastroenterology, dept. of Int Medicine Affiliated Hospital University of Oslo, Østfold Fredrikstad

Helse Fonna HF Haugesund Sjukehus Kirurgisk - vest blokk gastro

Ullevål Hospital

Stavanger Hospital

Halmstad Hospital

Dept of Surgery, University Hospital Malmö

Does Glyceryl Nitrate Prevent Post-Endoscopic Retrograde Cholangiopancreaticography (ERCP) Pancreatitis?

Hvidovre University Hospital

cardiac tamponade

misselijkheid

nausea

cardiac tamponade/misselijkheid

Sternal Block With Liposomal Bupivacaine vs. Saline Prior to Incision in Cardiac Surgery

Does Glyceryl Nitrate Prevent Post-Endoscopic Retrograde Cholangiopancreaticography (ERCP) Pancreatitis?

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