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carrageenan/atrofie

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Bladzijde 1 van 43 resultaten

Follistatin alleviates synovitis and articular cartilage degeneration induced by carrageenan.

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Activins are proinflammatory cytokines which belong to the TGFβ superfamily. Follistatin is an extracellular decoy receptor for activins. Since both activins and follistatin are expressed in articular cartilage, we hypothesized that activin-follistatin signaling participates in the process of joint

Skeletal muscle weakness caused by carrageenan-induced inflammation.

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BACKGROUND The skeletal muscle weakness associated with many chronic diseases has been attributed to the catabolic effect of pro-inflammatory cytokines. We aimed to determine if local muscle inflammation has direct affects on contractile function and contributes to muscle weakness independent of
Aims: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) causes long-standing pain and/or storage symptoms. This study aimed to evaluate the likelihood of deterioration of bladder sensation in a carrageenan-induced CP/CPPS model
Animal experiments were performed to answer the question whether ulcerative colitis is predisposed to malignant degeneration. Male Wistar rats were given aqueous solutions of degraded Carrageenan (4%; w/v). After induction of ulcerative colitis, 1,2-Dimethylhydrazine (DMH; 132 mg/kg body weight) was

An ultrastructural study of the macrophages of the carrageenan-induced granuloma in the rat lung.

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The intralobular injection of 0.17 ml of 2 per cent. carrageenan into the rat lung induced an inflammatory granulomatous response. This inflammation was characterized in the early stages by immediate polymorphonuclear (PMN) leucocyte infiltration into the alveoli. Within 2 days the PMN's began to

Multifunctional effects of anticomplementary agent K-76 on carrageenan-induced colitis in the rabbit.

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In this study the effect of K-76, a sesquiterpene compound with anticomplementary activity isolated from a fungus culture, on carrageenan-induced colitis was studied from biochemical, histological and immunohistopathological aspects. K-76 suppressed epithelial cell loss, crypt abscess formation,
OBJECTIVE Inflammation following a knee injury is one of the factors associated with initiation of cartilage degeneration leading to osteoarthritis (OA). The hypothesis tested was that inflammation results in elevated expression of proteinases implicated in OA. METHODS Mature female rabbits received

Role of nitric oxide during carrageenan-sensitized endotoxin shock in mice.

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We have previously clarified that sensitization with a sulfated polygalactose, carrageenan (CAR), enhances endotoxin-induced tumor necrosis factor (TNF) production and lethality in mice. The present study was performed to examine the role of nitric oxide (NO) in CAR-sensitized septic mice with two

Inhibitory Effects of Carrageenans on Endotoxin-Induced Inflammation.

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The inhibitory effects of carrageenans (CRGs) on lipopolysaccharide (LPS) induced inflammation in a mouse model of endotoxemia and in complex therapy of patients with enteric infections of Salmonella etiology were studied. The atomic force microscopy (AFM) examination of LPS and its mixture with
BACKGROUND Evaluate the potential role of p38 inhibitors for the treatment of osteoarthritis using an animal model of joint degeneration (iodoacetate-induced arthritis) and a pain model (Hargraeves assay). METHODS P38 kinase activity was evaluated in a kinase assay by measuring the amount of
The objective of the present study was to investigate the effect of the fucoxanthin (FUCO) alone and in combination with glucosamine hydrochloride (GAH) on carrageenan/kaolin-induced inflammatory arthritis model in rats and to explore its underlying mechanisms. Joint swelling, muscle weight ratio

Electrical impedance myography for the detection of muscle inflammation induced by λ-carrageenan.

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Electrical impedance myography (EIM) is a technique for the assessment of muscle health and composition and has been shown to be sensitive to a variety of muscle pathologies including neurogenic atrophy and connective tissue deposition. However, it has been minimally studied in pure inflammation. In

[Histochemical aspects in carrageenan induced inflammation].

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Some changes of groundsubstance and cell proliferation are histochemically demonstrated in the carrageenin induced edema, in the connective tissue of the rat hund paw. We observed, that the leucocytic infiltration (beginning 5 minutes after inflammation) and the desintegration of these cells,

The anti-inflammatory and hepatoprotective effects of fractions from Cudrania cochinchinensis var. gerontogea.

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Various fractions of the ethanol extract from the root wood of Cudrania cochinchinensis var. gerontogea (Moraceae) were evaluated for their anti-inflammatory effects on carrageenan-induced edema and hepatoprotective activities on carbon tetrachloride (CCl4)-induced and D-galactosamine-(D-GalN)

A comprehensive evaluation of the toxicology of cigarette ingredients: essential oils and resins.

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BACKGROUND A total of 32 essential oils and resins were added individually to experimental cigarettes. OBJECTIVE A battery of tests was used to compare the toxicity of mainstream smoke from these experimental cigarettes. The lowest target inclusion level was 100 ppm and the highest was 100,000
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