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Blood smear analysis in babesiosis, ehrlichiosis, relapsing fever, malaria, and Chagas disease.

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Blood smear analysis is especially useful for diagnosing five infectious diseases: babesiosis, ehrlichiosis, relapsing fever due to Borrelia infection, malaria, and American trypanosomiasis (Chagas disease). It should be performed in patients with persistent or recurring fever or in those who have

[Anatomoclinical correlation. Case 1/03 - male, 27 years-old, with reagent serology for Chagas disease and history of rheumatic fever for 11 years (Pontifícia Universidade Católica - Campinas, SP)].

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Fatal acute Chagas disease by Trypanosoma cruzi DTU TcI, Ecuador.

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Chagas disease is caused by the haemoflagellate protozoan Trypanosoma cruzi. Currently, T. cruzi recognizes seven discrete typing units (DTUs): TcI to TcVI and Tcbat. The genetic diversity of T. cruzi is suspected to influence the clinical outcome. Acute clinical manifestations, which

Presence of Acute Chagas Disease Among Febrile Patients in the Western Coast of Mexico

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Chagas disease (ChD) is a parasitosis caused by the protozoan Trypanosoma cruzi (Tc). It is endemic to almost all Latin American countries, including the southern United States. The acute form of ChD and its actual incidence have rarely been described in Mexico, despite the extensive presence

Cross-reactivity between antibodies in the sera of individuals with leishmaniasis, toxoplasmosis, and Chagas' disease and antigens of the blood-stage forms of Plasmodium falciparum determined by indirect immunofluorescence.

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Seroepidemiologic studies using the indirect immunofluorescent antibody test (IFAT) are valuable in malaria control programs in identifying local foci of malaria, in diagnosing malaria in asymptomatic, low-parasitemia blood donors in nonendemic countries, in detecting imported malaria and preventing

Heart transplantation in patients with Chagas' disease cardiomyopathy.

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Among 26 heart transplant patients, four had Chagas' disease cardiomyopathy. They were male patients, aged 28 to 43 years; three were in New York Heart Association class IV, and one was in class II but with refractory arrhythmias. The immunosuppressive protocol was cyclosporine and steroids in the

Acquired cell-mediated immunodepression in acute Chagas' disease.

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In this study two groups of patients with acute Chagas' disease were identified. Group one consisted of five patients with apparent acute Chagas' disease. These patients showed symptoms and signals of an acute illness, such as high fever and enlarged spleen. One of these patients developed severe

Vimentin and Anti Vimentin Antibodies in Chagas' Disease.

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Vimentin is a main structural protein of the cell, a component of intermediate cell filaments and immersed in cytoplasm. Vimentin is mimicked by some bacterial proteins and anti-vimentin antibodies occur in autoimmune cardiac disease, as rheumatic fever. In this work we studied vimentin distribution

The discovery of Chagas' disease and the formation of the early Chagas' disease concept.

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This paper attempts to show how leading contemporary disciplines influenced the discovery of Chagas' disease and the formation of the early disease concept. Chagas was among the first generation of Brazilian trained scientists who incorporated modern principles of tropical medicine in its research.

Acute Chagas' disease in western Venezuela: a clinical, seroparasitologic, and epidemiologic study.

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A clinical, parasitologic, and serologic study carried out between 1988 and 1996 on 59 acute-phase patients in areas of western Venezuela where Chagas' disease is endemic showed 19 symptomatic patterns or groups of symptoms appearing in combination with different frequencies. The symptomatic pattern

Plasmid DNA immunization with Trypanosoma cruzi genes induces cardiac and clinical protection against Chagas disease in the canine model.

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The only existing preventive measure against American trypanosomosis, or Chagas disease, is the control of the transmitting insect, which has only been effective in a few South American regions. Currently, there is no vaccine available to prevent this disease. Here, we present the clinical and

Evaluation of an autoimmune type antibody in the sera of patients with Chagas' disease.

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Utilizing cryostat sections of mouse heart as antigen, antibodies in the sera of patients with Chagas' disease were investigated for autoimmune-type interation. Sera from 47 normal, 70 patients with various contagious diseases, 116 sera from persons with leishmaniasis, and 90 from persons with

FIRST REPORT OF ACUTE CHAGAS DISEASE BY VECTOR TRANSMISSION IN RIO DE JANEIRO STATE, BRAZIL.

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Chagas disease (CD) is an endemic anthropozoonosis from Latin America of which the main means of transmission is the contact of skin lesions or mucosa with the feces of triatomine bugs infected by Trypanosoma cruzi. In this article, we describe the first acute CD case acquired by vector transmission

Emerging acute Chagas disease in Amazonian Brazil: case reports with serious cardiac involvement.

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Four cases of serious cardiac attacks by autochthonous Trypanosoma cruzi infection from the Brazilian Amazon are reported; three of them occurred in micro-epidemic episodes. The manifestations included sudden fever, myalgia, dyspnea and signs of heart failure. Diagnosis was confirmed by specific

[Chagas disease: clinical aspects and treatment in non-endemic countries].

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International migration has led to the emergence of Chagas disease in industrialized countries, notably France. Clinicians should consider and test for Chagas disease in several situations: chronic cardiac and digestive manifestations in patients who lived (or whose parents lived) in an endemic

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