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choline acetyltransferase/cariës
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Neurochemical anatomy of fetal hippocampus transplanted into large lesion cavities made in the adult rat brain.
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The purpose of the present study was to determine whether neurochemicals normally found within neuron somata, fibers, and terminals of the hippocampal formation would also be present in transplanted hippocampal tissue that had developed in lesion cavities made in adult rat brains by aspiration of
Choline acetyltransferase activity in rat heart after transplantation.
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Choline acetyltransferase (CAT) catalyzes the biosynthesis of acetylcholine according to the chemical equation: Acetyl-CoA + Choline in equilibrium Acetylcholine + CoA. To demonstrate the neuronal relationship of this enzyme, CAT activity was measured in hearts to which the extrinsic innervation was
Acetylcholinesterase and choline acetyltransferase staining of neurons in the opossum esophagus.
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The purpose of the present investigation was to identify and compare cholinergic intramural neurons in the lower esophageal sphincter and esophageal body by histochemical staining for acetylcholinesterase and the enzyme that synthesizes acetylcholine, choline acetyltransferase. Opossums were
Spinally projecting preproglucagon axons preferentially innervate sympathetic preganglionic neurons.
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Glucagon-like peptide-1 (GLP-1) affects central autonomic neurons, including those controlling the cardiovascular system, thermogenesis, and energy balance. Preproglucagon (PPG) neurons, located mainly in the nucleus tractus solitarius (NTS) and medullary reticular formation, produce GLP-1. In
The influence of mechanical injury on the metabolic activity of transplanted cerebral cortex.
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The authors studied the metabolic activity of rat embryonic cerebral cortex grafts (ED 15-16) implanted into rat brains immediately (TR0) and 14 days (TR14) after cavity formation. Over a period of two months, the ATP, lactate and glucose concentration in TR0 transplants remained at the same level
Innervation of embryonic hippocampal implants by regene-rating axons of cholinergic septal neurons in the adult rat.
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The regeneration of the septal cholinergic system in adult rats has been studied in animals bearing transplants of hippocampus taken from 20-40 mm rat fetuses (approximately 17-21 days of gestation). The septal axons located within the fimbria and the dorsal fornix were lesioned and a cavity was
Regeneration of the septohippocampal pathways in adult rats is promoted by utilizing embryonic hippocampal implants as bridges.
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The ability of embryonic hippocampal tissue to promote regeneration of cholinergic axons in the septohippocampal system has been studied in adult rats. Strips of embryonic hippocampus, taken from 7-40 mm rat fetuses, were implanted into a 2-3 mm wide cavity which completely transected the septal
Morphologic features of embryonic neocortex grafts in adult rats following frontal cortical ablation.
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Embryonic cortex from 19-day fetuses was transplanted in a medial frontal cortex wound cavity of 105-day-old male rats. Nissl-stained tissue revealed little internal laminar organization. Graft sections impregnated by the Loyez method exhibited bands of myelinated fibers surrounding implants as well
Septal fetal tissue transplants restore long-term potentiation in the dentate gyrus of fimbria-formix-lesioned rats.
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Two groups of Sprague-Dawley male rats received bilateral aspirative lesions of the fimbria fornix under chloral hydrate anesthesia. One group (n = 9) received no further treatment (lesioned). In the second group (n = 8), a piece of septal fetal tissue, obtained at day E15-16, was implanted into
Target-independent diversification and target-specific projection of chemically defined retinal ganglion cell subsets.
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In diverse vertebrate species, defined subsets of retinal ganglion cells (RGCs, the neurons that project from retina to brain) are distinguishable on the basis of their dendritic morphology, physiological properties, neurotransmitter content and synaptic targets. Little is known about when this
Expression of L1 and PSA during sprouting and regeneration in the adult hippocampal formation.
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The objective of the present study was to evaluate the expression of polysialic acid (PSA) and the cell adhesion molecule L1 during axonal regeneration and sprouting after injury to the adult rat brain. All animals received a complete lesion of the fimbria-fornix (FF). Grafts of nerve growth factor
Human conditionally immortalized neural stem cells improve locomotor function after spinal cord injury in the rat.
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BACKGROUND
A growing number of studies have highlighted the potential of stem cell and more-differentiated neural cell transplantation as intriguing therapeutic approaches for neural repair after spinal cord injury (SCI).
METHODS
A conditionally immortalized neural stem cell line derived from human
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