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The contents of the text file named SYPA-003_C04US_SeqList_ST25.txt, which was created on Jun. 17, 2015 and is 107 KB in size, are hereby incorporated by reference in their entirety.
FIELD OF THE INVENTION
The present invention relates to the therapeutic use of guanylate cyclase C (GC-C) agonists as
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FIELD OF THE INVENTION
The present invention relates to the therapeutic use of guanylate cyclase C (GC-C) agonists as for reducing absorption of fat, triglycerides, bile acids and cholesterol. The agonists may be used either alone or in combination with inhibitors of cholesterol biosynthesis in the
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TECHNICAL FIELD OF THE INVENTION
The present invention relates generally to the field of human genetics. The present invention specifically relates to a human coronary heart disease susceptibility gene (CHD1), some alleles of which are related to susceptibility to coronary heart disease. More
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FIELD OF THE INVENTION
The present invention relates to medicine technology, and more specifically, it relates to a new use of HMG-CoA reductase inhibitor (statins compound) locally used for prevention and treatment of diabetes, obesity, hypertension, hyperlipidemia, artheroslerosis, cardiovascular
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This is a U.S. National Phase entry based on PCT/CN2013/001429 filed Nov. 22, 2013, which respectively claiming priority to Chinese patent application 20120512630.8 filed Nov. 23, 2012 and Chinese patent application 201310426327.0 filed Sep. 18, 2013.
FIELD OF THE INVENTION
The present invention
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This patent disclosure contains material that is subject to copyright protection. The copyright owner has no objection to the facsimile reproduction by anyone of the patent document or the patent disclosure as it appears in the U.S. Patent and Trademark Office patent file or records, but otherwise
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FIELD OF THE INVENTION
The present invention relates to novel thyroid receptor ligands and, more particularly, relates to novel cyano containing oxamic acids, and derivatives thereof, which are useful in the treatment of obesity, hyperlipidemia, thyroid disease, hypothyroidism and related disorders
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FIELD OF THE INVENTION
The present invention relates to novel thyroid receptor ligands and, more particularly, relates to novel oxamic acids, and derivatives thereof, which are useful in the treatment of obesity, hyperlipidemia, glaucoma, cardiac arrhythmia, skin disorders, thyroid disease,
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FIELD OF THE INVENTION
The present invention relates to novel thyroid receptor ligands and, more particularly, relates to novel oxamic acids, and derivatives thereof, which are useful in the treatment of obesity, hyperlipidemia, glaucoma, cardiac arrhythmia, skin disorders, thyroid disease,
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This application is the National Stage of Application No. PCT/US07/64974 filed Mar. 27, 2007, which claims benefit under 35 U.S.C. .sctn.119(e) of U.S. Provisional Application No. 60/787,104, filed Mar. 29, 2006, the contents of which are incorporated herein by reference in their entirety.
The
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RELATED APPLICATIONS
This application is a 35 U.S.C. .sctn.371 national phase application of PCT/KR2011/000098 (WO 2011/083999), filed on Jan. 6, 2011, entitled "BIGUANIDE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS AN ACTIVE INGREDIENT", which
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TECHNICAL FIELD
The present invention relates to a biguanide derivative exhibiting excellent effects on activation of 5'-AMP-activated protein kinase (AMPK) and inhibition of cancer cell proliferation in a low dose compared to conventional drugs, a method of preparing the same, and a pharmaceutical
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TECHNICAL FIELD
The present invention relates to a biguanide derivative exhibiting excellent effects on activation of 5'-AMP-activated protein kinase(AMPK) and inhibition of cancer cell proliferation in a low dose compared to conventional drugs, a method of preparing the same, and a pharmaceutical
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TECHNICAL FIELD
The present invention relates to a biguanide derivative exhibiting excellent effects on activation of 5'-AMP-activated protein kinase (AMPK) and inhibition of cancer cell proliferation in a low dose compared with conventional drugs, a method of preparing the same, and a
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RELATED APPLICATIONS
This application is a 35 U.S.C. .sctn.371 national phase application of PCT/KR2011/000097 (WO2011/083998), filed on Jan. 6, 2011, entitled "Biguanide Derivative, A Preparation Method Thereof And A Pharmaceutical Composition Containing The Biguanide Derivative As An Active
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