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Investigations onboard the biosatellite Cosmos-1667.

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The program of the 7-day flight of the biosatellite Cosmos-1667 launched in July 1985 included experiments on two rhesus monkeys, ten Wistar SPF rats, ten newts, Drosophila flies, maize seedlings, lettuce sprouts, and unicellular organisms--Tetrahymena. The primate study demonstrated that transition

Investigations on biosatellites of the Cosmos series.

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Over the past decade, the USSR has launched six biosatellites of the Cosmos series. The first biosatellite flew 6 d; the remaining five flew 18-21 d. The principal purpose of this investigation was to continue studies on the adaptation of living systems to weightlessness; to investigate the

Cardiac morphology after conditions of microgravity during COSMOS 2044.

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Light- and electron-microscopic studies were performed on cardiac muscle from rats flown on COS-MOS 2044 and from four control groups. Average cross-sectional area of myofibers was measured by video analysis of the light-microscopic images of papillary and ventricular muscle samples from all

[Morphologic and cytochemical research aboard the biosatellite "Cosmos-782"].

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Organs of rats flown for 19.5 days on board the Cosmos-782 biosatellite were investigated morphologically and cytochemically. After flight, as a result of drastic decrease or loss of static load on the musculeskeletal system in zero-g, the rats developed mineral metabolism changes that

Morphometrical evaluation of myocardium from rats flown on biosatellite Cosmos-1887.

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The myocardium of rats kept on the biosatellite Cosmos-1887 for 13 days was morphometrically examined at the cellular and subcellular levels. It was found that weightlessness causes in the heart muscle cells atrophy of the muscle fibers, thinning of the sarcomeres a decrease in the relative volume

Cosmos 1887: morphology, histochemistry, and vasculature of the growing rat tibia.

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Light microscopy, electron microscopy, and enzyme histochemistry were used to study the effects of spaceflight on metaphyseal and cortical bone of the rat tibia. Cortical cross-sectional area and perimeter were not altered by a 12.5-day spaceflight in 3-month-old male rats. The endosteal osteoblast

Structural and metabolic properties of rat muscle exposed to weightlessness aboard Cosmos 1887.

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Male Wistar rats were subjected to 12.5 days of weightlessness aboard Cosmos 1887. Histomorphometric and biochemical analyses were investigated in soleus (SOL), plantaris (PL) and extensor digitorum longus (EDL) muscles of flight rats (group F) and compared with data from two groups of terrestrial

[Examination of skeletal muscles of rats after a short-term flight on Cosmos-1667].

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Using morphological and histochemical methods, skeletal muscles (soleus, gastrocnemius), quadriceps and biceps muscles) of Wistar-SPF rats flown for 7 days on Cosmos-1667 were investigated. The short-term exposure to microgravity led to muscle atrophy which primarily involved myofibers with a high

[Conditioned reflex activity of rats at later periods after the end of flight aboard the bioasatellite "Cosmos-605"].

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During the period from the 15th to the 50th day after the end of the flight in the "Cosmos-605" biosatellite, the rats revealed a deterioration of the capacity for the transfer of experience and for improving the habit of reaching the goal in a maze. There was also a change in the dynamics of errors

Artocarpus altilis extracts as a food-borne pathogen and oxidation inhibitors: RSM, COSMO RS, and molecular docking approaches

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Lipid oxidation and microbial contamination are the major factors contributing to food deterioration. Food additives like antioxidants and antibacterials can prevent food spoilage by delaying oxidation and preventing the growth of bacteria. Artocarpus altilis leaves exhibited biological properties

The Effect of a Multicomponent Intervention on Quality of Life in Residents of Nursing Homes: A Randomized Controlled Trial (COSMOS).

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To investigate if the multicomponent intervention of the COSMOS trial, combining communication, systematic pain management, medication review, and activities, improved quality of life (QoL) in nursing home patients with complex needs.Multicenter,

Budesonide/formoterol maintenance and reliever therapy in Asian patients (aged ≥16 years) with asthma: a sub-analysis of the COSMOS study.

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BACKGROUND The combination of an inhaled corticosteroid (ICS), budesonide, and a rapid long-acting β(2)-agonist (LABA), formoterol, in a single inhaler for use as maintenance and reliever therapy (Symbicort Turbuhaler SMART™) effectively achieves a high level of asthma control and reduces

The effect of space flight on the board of the satellite Cosmos 2044 on plasma hormone levels and liver enzyme activities of rats.

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The aim of present experiment was to study the changes of corticosterone, insulin and glucose levels in plasma, of the activity of enzymes involved in aminoacid metabolism in liver and the binding of insulin to specific receptors of cell membrane from liver and also of adipose tissue of rats exposed

Less Is More: The Impact of Deprescribing Psychotropic Drugs on Behavioral and Psychological Symptoms and Daily Functioning in Nursing Home Patients. Results From the Cluster-Randomized Controlled COSMOS Trial

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Objective: To investigate the impact of medication reviews using collegial mentoring and systematic clinical evaluation on psychotropic prescriptions, behavioral and psychological symptoms of dementia (BPSD), and activities of daily

Effects of spaceflight in the adductor longus muscle of rats flown in the Soviet Biosatellite COSMOS 2044. A study employing neural cell adhesion molecule (N-CAM) immunocytochemistry and conventional morphological techniques (light and electron microscopy).

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The effects of spaceflight upon the "slow" muscle adductor longus were examined in rats flown in the Soviet Biosatellite COSMOS 2044. The techniques employed included standard methods for light microscopy, neural cell adhesion molecule (N-CAM) immunocytochemistry and electron microscopy. Light

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