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diabetic nephropathies/oedeem

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9 resultaten

Substituted spirobenzazepines

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FIELD OF THE INVENTION This invention relates to novel nonpeptide substituted spirobenzazepines useful as, for example, vasopressin receptor antagonists. BACKGROUND OF THE INVENTION Vasopressin is a nonpeptide hormone that is secreted primarily from the posterior pituitary gland. The hormone effects

Substituted spiroheterocycles

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FIELD OF THE INVENTION This invention relates to novel nonpeptide substituted spiroheterobenzazepines useful as, for example, vasopressin receptor antagonists. BACKGROUND OF THE INVENTION Vasopressin is a nonapeptide hormone that is secreted primarily from the posterior pituitary gland. The hormone

Substituted spiroheterocycles

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FIELD OF THE INVENTION This invention relates to novel nonpeptide substituted spiroheterobenzazepines useful as, for example, vasopressin receptor antagonists. BACKGROUND OF THE INVENTION Vasopressin is a nonapeptide hormone that is secreted primarily from the posterior pituitary gland. The hormone

rAAV vector compositions, methods for targeting vascular endothelial cells and use in treatment of type I diabetes

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NAMES OF THE PARTIES TO A JOINT RESEARCH AGREEMENT Not Applicable. BACKGROUND OF THE INVENTION Field of the Invention The present disclosure relates generally to the fields of molecular biology and virology, and in particular, to the development of gene delivery vehicles. Disclosed are improved

Guanidine compound

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TECHNICAL FIELD The present invention relates to a guanidine compound which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for preventing and/or treating vascular adhesion protein-1 (hereinafter abbreviated as VAP-1)-related

Guanidine compound

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TECHNICAL FIELD The present invention relates to a guanidine compound which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for preventing and/or treating vascular adhesion protein-1 (hereinafter abbreviated as VAP-1)-related

Guanidine compound

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TECHNICAL FIELD The present invention relates to a guanidine compound which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for preventing and/or treating vascular adhesion protein-1 (hereinafter abbreviated as VAP-1)-related

Methods for treatment of nephrotic syndrome and related conditions

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FIELD OF THE DISCLOSURE The present disclosure is directed to methods for the treatment and prevention of nephrotic syndrome and conditions related thereto, such as, but not limited to, proteinuria and edema. BACKGROUND Nephrotic syndrome (NS) is a general term that refers to the loss of protein in

Methods for treatment of nephrotic syndrome and related conditions

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FIELD OF THE DISCLOSURE The present disclosure is directed to methods for the treatment and prevention of nephrotic syndrome and conditions related thereto, such as, but not limited to, proteinuria and edema. BACKGROUND Nephrotic syndrome (NS) is a general term that refers to the loss of protein in
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