diazepam/versterkte bloedingsneiging

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Xylazine-/diazepam-ketamine and isoflurane differentially affect hemodynamics and organ injury under hemorrhagic/traumatic shock and resuscitation in rats.

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Most experimental studies on hemorrhage and trauma are performed under anesthesia. We determined the effects of three commonly used anesthetic regimens on hemodynamics and organ damage under normal and hemorrhagic/traumatic shock (HTS) conditions in rats. Animals were anesthetized with

[Effect of diazepam (Valium) on the course of hemorrhagic shock in rabbits].

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[Intravenous diazepam in preventing postpartum bleeding caused by weak uterine contraction].

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Teratogenic effects of diazepam in the hamster.

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Pregnant hamsters were treated with different doses of oral and intravenous diazepam during the period of organogenesis. Teratogenic effects of diazepam were observed following oral treatment on days 8 and 10 and following intravenous treatment on day 11 of gestation. Types of malformations included

Warfarin-fluoxetine and diazepam-fluoxetine interaction.

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Fluoxetine and its metabolite norfluoxetine are eliminated by oxidative metabolism via the CYP450 system and may inhibit the oxidative metabolism of other drugs to various degrees. A fluoxetine-warfarin interaction has been postulated, but is not well documented in the literature. The elimination of

Sedative efficacy of droperidol and diazepam in the rat.

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Droperidol and diazepam were evaluated for sedative properties in 12 male Sprague Dawley rats (Rattus norvegicus). Over a period of several weeks, each rat was treated subcutaneously with 0.5 mg droperidol/kg, 2.0 mg droperidol/kg, 5.0 mg diazepam/kg, 15.0 mg diazepam/kg, and physiologic saline

The diagnosis of the site of upper gastrointestinal haemorrhage in patients with established portal hypertension.

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Seventy-five endoscopies were performed in 60 patients known to have oesophageal varices presenting with further upper gastrointestinal haemorrhage during the previous 72 hours. A site of active bleeding was found at 50 of 75 examinations (67 percent) including all 21 patients endoscoped within

[Improvement in hemiballism after transient hypoxia in a case of subthalamic hemorrhage].

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A 73-year-old man was admitted complaining of violent involuntary movement in the left upper and lower extremities. He had a ten-year history of hypertension and had had a left thalamic hemorrhage 6 years before admission. On neurological examination Horner's sign in the right eye, typical

Evaluation of induction by use of a combination of oxymorphone and diazepam or hydromorphone and diazepam and maintenance of anesthesia by use of isoflurane in dogs with experimentally induced hypovolemia.

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OBJECTIVE To compare induction with hydromorphone and diazepam (HydroD) or oxymorphone and diazepam (OxyD) followed by maintenance with isoflurane in dogs with induced hypovolemia. METHODS 6 healthy mixed-breed dogs. METHODS The study used a crossover design. Measurements were obtained in

Determination of diazepam and its pharmacologically active metabolites in blood by bond Elut column extraction and reversed-phase high-performance liquid chromatography.

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A rapid and quantitative analytical micro method for the determination of diazepam and its major pharmacologically active metabolites utilizing high-performance liquid chromatography (HPLC) is reported. The drug and its metabolites were extracted from 50-100 microliter samples of whole blood, serum

Comparison of paracetamol and aminophenazone plus diazepam suppositories for anxiety and pain relief after tonsillectomy in children.

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The anxiety and pain-relieving effect of paracetamol 10 mg/kg or a combination of aminophenazone 4 mg/kg and diazepam 0.2 mg/kg suppositories was studied in 82 children after tonsillectomy in a double-blind study. Both suppositories were studied after halothane or enflurane anaesthesia. At 30 min

Efficacy and safety of premedication with oral ketamine for day-case adenoidectomy compared with rectal diazepam/diclofenac and EMLA.

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BACKGROUND Because of its pain-attenuating and sedative properties oral ketamine has been used as premedication in children and adults. We wanted to compare in children scheduled for adenoidectomy safety and efficacy of oral ketamine with a premedication that causes similar preoperative sedation and

Effect of narcotic agents and of bleeding on systemic and renal haemodynamics in healthy and CCl4-treated cirrhotic rats.

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1. The haemodynamic effects of different narcotic agents have been tested in healthy rats and in rats with cirrhosis. 2. Pentobarbital suppresses the sympathetic nervous system. Susceptibility to ketamine is unpredictable, leading to both insufficient pain relief and narcosis related mortality. The

Prevention of upper gastrointestinal hemorrhage in 582 burned children.

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In 582 burned children, neutralization of gastric acid and reduction of psychic stress were utilized to reduce upper gastrointestinal ulceration and hemorrhage. While receiving milk, diazepam, and psychologic support, two children required operation. Two of the children who died without clinically

Colonoscopy in children with bleeding per rectum.

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There are few reports of colonoscopy in children. Twenty-six children with bleeding per rectum were examined colonoscopically to determine the aetiology of the bleeding. A total of 32 colonoscopies were performed. Except for 5 children who needed general anaesthesia, all the rest were performed with

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