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Bladzijde 1 van 25 resultaten
Composition with a fungal (yeast) lipase and method for treating lipid malabsorption in cystic fibrosis as well as people suffering from pancreatic lipase insufficiency
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to a composition and method for treating pancreatic enzyme insufficiency, particularly lipid malabsorbtion associated with cystic fibrosis.
2. Description of Related Art
Various diseased states such as pancreatitis,
Peptoid and nonpeptoid containing .alpha.-keto oxadiazoles as serine protease inhibitors
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BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes, which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin. These proteases have in common a catalytic triad consisting of Serine-195, Histidine-57 and Aspartic acid-102(chymotrypsin numbering system). Human
Peptoid and nonpeptoid containing alpha-keto oxadiazoles as serine protease inhibitors
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BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes, which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin. These proteases have in common a catalytic triad consisting of Serine-195, Histidine-57 and Aspartic acid-102(chymotrypsin numbering system). Human
Protease variants for pharmaceutical use
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REFERENCE TO A SEQUENCE LISTING
This application contains a Sequence Listing in computer readable form. The computer readable form is incorporated herein by reference.
TECHNICAL FIELD
The present invention relates to a protease having at least 90% identity to amino acids 1-188 of SEQ ID NO: 1, and
Serine protease inhibitors-N-substituted derivatives
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The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin.
Serine protease inhibitors-keto and di-keto containing ring systems
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The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes which include elastase, chymotrypsin, cathepsin G, trypsin and thrombin.
Val-pro containing .alpha.-keto oxadiazoles as serine protease inhibitors
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BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes, which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin. These proteases have in common a catalytic triad consisting of Serine-195, Histidine-57 and Aspartic acid-102 (chymotrypsin numbering system). Human
Indole and tetrahydroisoquinoline containing Alpha-keto oxadiazoles as serine protease inhibitors
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The present invention relates to certain substituted oxadiazole nonpeptides, which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes, which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin. These proteases have in
Serine protease inhibitors-proline analogs
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The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin.
Serine protease inhibitors
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The present invention relates to certain substituted oxadiazole nonpeptides, which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes, which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin. These proteases have in
Serine protease inhibitor--tripeptoid analogs
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The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin.
Serine protease inhibitors-cycloheptane derivatives
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BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin. These proteases have in common a catalytic triad consisting of Serine-195, Histidine-57 and Aspartic acid-102 (chymotrypsin numbering system). Human
Combined biomarker measurement of fibrosis
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BACKGROUND OF THE INVENTION
Technical Field of the Invention
The present invention relates in a first aspect to a monoclonal antibody which is specifically reactive with the C-terminal neo-epitope of PIIINP, and its use in a method of immunoassay for detecting and quantifying PIIINP. In a further
Modulators of protease activated receptors
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CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is the United States National Phase of PCT Application No. PCT/AU2012/000891, filed Jul. 27, 2012, which claims priority to PCT/AU2011/000959, filed Jul. 28, 2011, and to AU 2011904617, filed Nov. 7, 2011, the entire contents of each of
Lipase variants for pharmaceutical use
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REFERENCE TO A SEQUENCE LISTING
This application contains a Sequence Listing in computer readable form. The computer readable form is incorporated herein by reference.
TECHNICAL FIELD
The present invention relates to a lipase for use as a medicament, which lipase (a) has at least 50% identity to the
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