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Bladzijde 1 van 246 resultaten
A series of novel neuroprotective blood brain barrier penetrating flavonoid drugs to treat acute ischemic stroke.
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Stroke is the 4th leading cause of death and disability in adults in the USA. However, in the majority of patients, the detrimental effects of an ischemic insult go untreated because of the lack of efficacious neuroprotective compounds. Using naturally occurring compounds as a building block to
Dietary flavonoid intake and incident coronary heart disease: the REasons for Geographic and Racial Differences in Stroke (REGARDS) study.
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Flavonoids are dietary polyphenolic compounds with a variety of proposed beneficial cardiovascular effects, but rigorous prospective studies that examine the association between flavonoid intake and incident coronary heart disease (CHD) in geographically and racially diverse US samples are
Dietary flavonoid intake and the risk of stroke: a dose-response meta-analysis of prospective cohort studies.
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To clarify and quantify the potential association between intake of flavonoids and risk of stroke.
Meta-analysis of prospective cohort studies.
Studies published before January 2016 identified through electronic searches using PubMed, Embase and the Cochrane Library.
Prospective cohort studies with
[Flavonoids of puerarin versus tanshinone II A for ischemic stroke: a randomized controlled trial].
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BACKGROUND
Flavonoids are widely used today in the treatment of ischemic stroke. The therapeutic effects and functions of flavonoids are, therefore, generating more and more interest.
OBJECTIVE
To investigate the therapeutic effects and functions of flavonoids of puerarin in treating patients with
Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study.
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BACKGROUND
Epidemiological studies suggested that consumption of fruit and vegetables may protect against stroke. The hypothesis that dietary antioxidant vitamins and flavonoids account for this observation is investigated in a prospective study.
METHODS
A cohort of 552 men aged 50 to 69 years was
Dietary flavonoids and risk of stroke in women.
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OBJECTIVE
To date, few studies have examined associations between the wide range of flavonoid subclasses and risk of ischemic, hemorrhagic, and total stroke.
METHODS
We conducted a prospective study among 69 622 women from the Nurses' Health Study. Total flavonoid and subclass intakes were
Tea, flavonoids and stroke in man and mouse.
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OBJECTIVE
To evaluate the strength of the in vivo evidence of relationships between flavonoids and risk of stroke.
METHODS
We reviewed the literature more broadly for flavonoids and stroke and conducted an evidence-based review of original publication experiments on tea or tea components on induced
Flavonoid intake and the risk of ischaemic stroke and CVD mortality in middle-aged Finnish men: the Kuopio Ischaemic Heart Disease Risk Factor Study.
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The role of flavonoids in CVD, especially in strokes, is unclear. Our aim was to study the role of flavonoids in CVD. We studied the association between the intakes of five subclasses (flavonols, flavones, flavanones, flavan-3-ols and anthocyanidins), a total of twenty-six flavonoids, on the risk of
Total Flavonoids in Caragana (TFC) Promotes Angiogenesis and Enhances Cerebral Perfusion in a Rat Model of Ischemic Stroke.
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Previous studies have demonstrated that total flavonoid extracts from Caragana sinica (TFC) exert multiple therapeutic effects, promote blood flow, and exhibit anti-inflammatory and antioxidant properties. The present study aimed to investigate whether TFC promotes angiogenesis and exerts
Flavonoids from Radix Scutellariae as potential stroke therapeutic agents by targeting the second postsynaptic density 95 (PSD-95)/disc large/zonula occludens-1 (PDZ) domain of PSD-95.
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Excessive activation of N-methyl-D-aspartate receptors (NMDARs) and subsequent production of nitric oxide by neuronal nitric oxide synthase (nNOS) contribute to neuronal damage resulting from hypoxic and ischemic insults. NMDARs and nNOS are coupled together at the postsynaptic membrane through
Intake of flavonoids, carotenoids, vitamins C and E, and risk of stroke in male smokers.
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OBJECTIVE
Antioxidants may protect against atherosclerosis and thus prevent cerebrovascular disease. We studied the association between dietary antioxidants and subtypes of stroke.
METHODS
The study cohort consisted of 26 593 male smokers, aged 50 to 69 years, without a history of stroke. They were
Neuroprotective effects of xanthohumol, a prenylated flavonoid from hops (Humulus lupulus), in ischemic stroke of rats.
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Xanthohumol is the principal prenylated flavonoid in hops (Humulus lupulus L.), an ingredient of beer. Xanthohumol was found to be a potent chemopreventive agent; however, no data are available concerning its neuroprotective effects. In the present study, the neuroprotective activity and mechanisms
Letter by Olie et al regarding article, "dietary flavonoids and risk of stroke in women".
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Rapid identification and analysis of the active components of traditional Chinese medicine Xiaoxuming decoction for ischemic stroke treatment by integrating UPLC-Q-TOF/MS and RRLC-QTRAP MSn method.
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Xiaoxuming decoction (XXMD) is a key Chinese medicine prescription, which has been clinically used for stroke treatment for thousands of years in ancient China. The extracted active fraction of XXMD (AF-XXMD) contains almost pharmacological active components with anti-cerebral ischemic effects.
The effect of Scutellaria baicalensis stem-leaf flavonoids on spatial learning and memory in chronic cerebral ischemia-induced vascular dementia of rats.
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Flavonoids have been shown to improve cognitive function and delay the dementia progression. However, the underlying mechanisms remain elusive. In the present study, we examined the effect of Scutellaria baicalensis stem-leaf total flavonoids (SSTFs) extracted from S. baicalensis Georgi on spatial
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