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The effects of newly synthesized pyrazole derivatives on formaldehyde-, carrageenan-, and dextran-induced acute paw edema in rats.

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The antiinflammatory effects of 10 newly synthesized pyrazole derivatives on formaldehyde-induced rat paw edema were investigated. The most effective of them (K-3) was investigated again in dextran- and carrageenan-induced paw edema. In formaldehyde-induced paw edema, K-3 50, 100, and 200 mg/kg p.o.

Carvedilol can attenuate histamine-induced paw edema and formaldehyde-induced arthritis in rats without risk of gastric irritation.

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OBJECTIVE Rheumatoid arthritis treatment aims to control joint damage and any associated complications such as cardiovascular disease. Most anti-inflammatory drugs have a high tendency to cause gastro-intestinal irritation. The present study is designed to investigate the anti-inflammatory effect of

Activities of 2-phthalimidethyl nitrate and 2-phthalimidethanol in the models of nociceptive response and edema induced by formaldehyde in mice and preliminary investigation of the underlying mechanisms.

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The activities of 2-phthalimidethyl nitrate (PTD-NO) and 2-phthalimidethanol (PTD-OH) were recently demonstrated in models of pain and inflammation. We expanded our investigation by evaluating their activities in models of nociceptive and inflammatory pain and inflammatory edema, the preliminary

[Effect of aliphatic sulfoxides as well as that of dicyclohexylsulfoxide on the formaldehyde and dextran induced edema of the rat paw].

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Studies on the acute inflammatory response. II. Influence of antihistaminics and catecholamines on formaldehyde-induced edema.

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[Enzyme activities in the edema fluid of rat paw edemas, induced by dextran, formaldehyde and Arthus reaction].

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Quantitative morphology of permeability lung edema in dogs induced by alpha-naphthylthiourea.

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In pulmonary edema, fluid accumulates first in the interstitium, then in the alveoli. However, the relative amounts of interstitial fluid around arteries and veins of different sizes are unknown; in addition, the effects of fixation on the light microscopic quantitation of edema are unclear. To

Formaldehyde inhalation triggers autophagy in rat lung tissues.

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Formaldehyde (FA), a ubiquitous environmental contaminant, has long been suspected of causing lung injury. However, the molecular and cellular mechanisms underlying this phenomenon remain elusive. The aim of this study was to elucidate the role of autophagy in lung injury induced by FA inhalation.

Smoke aldehyde component influences pulmonary edema.

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The pulmonary edema of smoke inhalation is caused by the toxins of smoke and not the heat. We investigated the potential of smoke consisting of carbon in combination with either acrolein or formaldehyde (both common components of smoke) to cause pulmonary edema in anesthetized sheep. Seven animals

Idiopathic intracranial hypertension. Lack of histologic evidence for cerebral edema.

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OBJECTIVE To study brain histologic features in two cases of idiopathic intracranial hypertension (pseudotumor cerebri) at autopsy. METHODS Formaldehyde solution-fixed sections of cerebral white matter in two cases and structures of the sensory visual system in one case were

[Intestinal edema caused by ingested formalin].

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A 65-yr-old man treated for depression was transferred to our hospital. He ingested over 150 ml of formalin for suicidal attempt. On admission, he was hypotensive, developing acute renal failure and liver dysfunction. During first 36 hours, he needed 21 l of lactate Ringer solutions to maintain

Dominantly inherited cystoid macular edema. A histopathologic study.

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BACKGROUND Dominantly inherited cystoid macular edema was described as a clinically distinct form of macular dystrophy with an onset at approximately age 30 years with slow progression over the ensuing decades. This is the first report of the light and electron microscopic findings in two donor eyes

Distribution of fluid in bronchovascular bundles with permeability lung edema induced by alpha-naphthylthiourea in dogs. A morphometric study.

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We utilized light microscopic morphometry to examine the distribution of fluid in bronchovascular bundles of different sizes. Permeability edema was induced in 10 anesthetized dogs with 27 mg/kg of alpha-naphthylthiourea. Eight dogs served as controls. After moderately severe edema, diagnosed on

Intravesicular formaldehyde instillation and renal complications.

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Intravesicular formaldehyde has been used for intractable hemorrhagic cystitis since the late 1960's. Initial reports described few complications, but in the 1970's both ureteral as well renal parenchymal damage were reported in the urology literature. This has been less appreciated by nephrologists

Pulmonary interstitial edema in the pig after heavy exercise.

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During exercise (especially in hypoxia), the alveolar-arterial O2 tension difference increases. This impairment of pulmonary gas exchange is caused partly by diffusion disequilibrium, but it has also been shown that an exercise-induced increase in ventilation-perfusion (VA/Q) inequality develops.

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