gibberellic acid/kanker

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Effect of gibberellic Acid on crown gall tumor induction in aging primary pinto bean leaves.

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Gibberellic acid was tested for its effect on tumor induction by Agrobacterium tumefaciens in primary pinto bean (Phaseolus vulgaris) leaves in various stages of development. The hormone was found to promote tumor induction in partially aged leaves but did not effect tumor induction in very young

Gibberellic acid, a plant growth regulator, increases mast cell recruitment and alters Substance P levels.

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Gibberellic acid (GA3), a plant growth regulator, is used commonly in agriculture. Its potential hazardous effects on human health, however, were relatively unexplored. Several studies demonstrated that in animals chronic GA3 consumption increased tumor formation and oxidative stress. Mast cells and

Morphogenic responses of debudded tobacco plants to gibberellic Acid and indole-3-acetic Acid.

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Stem applications of indole-3-acetic acid (IAA) or gibberellic acid (GA) did not prevent or alter tumor or teratoma formation in debudded tobacco plants (Nicotiana tabacum L., var. One Sucker). The materials produced intense (in case of GA) and moderate (in case of IAA) stem proliferations when

TRIM67 promotes NF‑κB pathway and cell apoptosis in GA‑13315‑treated lung cancer cells.

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13‑Chlorine‑3,15‑dioxy‑gibberellic acid methyl ester (GA‑13315), a gibberellin derivative, possesses strong anti‑tumor activity in vitro and in vivo. The present study aimed to investigate the underlying mechanisms of GA‑13315‑induced apoptosis in human non‑small cell lung cancer cell lines. Lung

Anti-tumor effects and mechanism of GA-13315, a novel gibberellin derivative, in human lung adenocarcinoma: an in vitro and in vivo study.

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To investigate the anti-tumor effects and the mechanism of the compound 13-chlorine-3, 15-dioxy-gibberellic acid methyl ester (GA-13315) in lung adenocarcinoma in vitro and in vivo.The antiproliferative effect of GA-13313 on the A549 cell line was

[Effect of plant hormones on the components of secretory pathway in human normal and tumor cells].

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Plant hormones play a key role in plant growth and differentiation. Many hormones are known as potential antitumor agents, yet others appear to affect the secretory activity and are produced by mammalian cells as pro-inflammatory cytokines. The goal of this research was to study the effect of

Production of tumour-inhibitory lignans in callus cultures of Podophyllum hexandrum.

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Callus cultures have been established from root explants of aseptically-grown Podophyllum hexandrum seedlings. A fully defined medium based on Gamborg's B5 salts supplemented with 2/4-dichlorophenoxyacetic acid, gibberellic acid and 6-benzylaminopurine was effective for both initiation and sustained

Callus formation versus differentiation of cultured barley embryos: hormonal and osmotic interactions.

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The effect of various plant growth substances as single agents was evaluated in a complex tissue culture system: whole embryo culture of early differentiating barley embryos. Callus formation in unsupplemented medium derives from the mesocotyl and is uniquely characteristic of cultures initiated at

Cloning and differential expression of QM like protein homologue from tea [Camellia sinensis (L.) O. Kuntze].

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The QM like protein gene encodes for ribosomal protein L10, which is implicated in tumor suppression, transcription factor regulation, and ribosome stability in yeast and mammals. Present study describes cloning of a full-length QM cDNA (CsQM) from tea leaves using differential display of mRNA

In vitro propagation of an endangered medicinal herb Chlorophytum borivilianum Sant. et Fernand. through somatic embryogenesis.

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Tuberous roots of Chlorophytum borivilianum Sant. et Fernand. which are a source of steroidal saponins, possess immunomodulatory, adaptogenic, aphrodisiac, antipyretic, diuretic, hemostatic and anti-tumour properties. Poor seed setting and germination and slow growth in conventional vegetative

Profiles of Little-Known Medicinal Polypores: Funalia trogii (Agaricomycetes).

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The purpose of this study was to comprehensively characterize little-known polypores that have recently been found to possess anticancer activity and thus can be used in targeted cancer therapy. Funalia trogii is a polypore with bipolar distribution and has been found by harvesters working in taiga

Antitumor and antiangiogenic effects of GA-13315, a gibberellin derivative.

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This study showed that 13-chlorine-3,15-dioxy-gibberellic acid methyl ester (GA-13315), a gibberellin derivative, possessed high antitumor and antiangiogenic activity in vitro and in vivo. Cytotoxicity assays showed that GA-13315 was a potential and efficient antitumor compound, with inhibitory

Characterization of Arabidopsis thaliana GCN2 kinase roles in seed germination and plant development.

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Eukaryotic GCN2 (general control nonderepressible 2) is a serine/threonine protein kinase that plays an essential role in modulating amino acid metabolism in response to nutrient deprivation. A wide spectrum of GCN2 functions in yeast and mammals has been characterized that spans from responses to

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