Graves Disease

1g/mL, 2 drops orally 3 times a day for 7 days before surgery

SSKI- Potassium Iodide

Columbia University Medical Center

Does Potassium Iodide (SSKI) Reduce Vascularity in Graves' Thyroidectomy?

Does the Use of Pre-operative SSKI Actually Reduce Vascularity and Improve Surgical Outcomes for Total Thyroidectomy in Graves' Disease?

Using 3D imaging software, the investigators will quantify the vascular flow in the ultrasound images and compare baseline images with the operating room (OR) images to assess if there is a difference in vascular flow between those timepoints. Vascular flow will be quantified using percent (%) surface area. This calculation will be done by a computer algorithm.

Jennifer Kuo

Assistant Professor of Surgery

Columbia University

All participants complete a baseline neck ultrasound no less than 7 days prior to surgery, to obtain vascular flow imaging. Participants are then randomized to receive 7 days of pre-operative SSKI or not receive any drug. In the practice at Columbia, all patients with Graves' disease receive SSKI preoperatively, though this is not standard practice across the country, thus the 'no drug' group is experimental for research.
All participants complete a second ultrasound on the operating table before surgery, to assess for change in vascularity (experimental, as not all patients receive intra-operative ultrasounds before surgery). Both ultrasounds are performed by the surgeon.

Iodine Deficiency Goiter

Infant Development

225 µg of iodine daily as a capsule of potassium iodide

Iodine capsule

450 g iodized salt provided for the household weekly. Salt iodine content was 30 to 40 mg iodine /kg salt as KIO3

Iodized Salt

Hawassa University

Community Salt Testing and Relation of Iodine Intake to Visual Information Processing of Ethiopian Infants

Barbara Stoecker

Regents Professor

Oklahoma State University

The mother-child dyads were randomly assigned either to receive iodine capsule (n = 53) or iodized salt (n = 53). The iodine capsule group received 225 µg of iodine daily as potassium iodide for 6 months.The iodized salt group was provided with iodized salt (30 to 40 mg iodine/kg as KIO3). One packet of salt (450 g) per household was provided starting within one week of delivery for 6 months.

iodine containing multivitamin
150 ug, 1 tablet daily

placebo, 1 tablet Daily of a non-iodine containing multivitamin

Thyroid Gland; Node

Lactation

The intervention is to give a multivitamin pill including 150 microgram iodine and compare with a multivitamin pill that is not including iodine.

iodine

Patients are given a non-iodine containing multivitamin tablet

Placebo

Health Care center

Iodine Status in Swedish Lactating Women - Effect of Iodine Supplementation in the Thyroid Function of Mother and Infant

A Double-blinded Randomised Study of Iodine Supplementation to Lactating Women in an Iodine-sufficient Area in Sweden and Evaluation of Maternal and Neonatal Iodine Levels and Thyroid Function

goiter/kalium

Does Potassium Iodide (SSKI) Reduce Vascularity in Graves' Thyroidectomy?

Community Salt Testing and Relation of Iodine Intake to Visual Information Processing of Ethiopian Infants

Iodine Status in Swedish Lactating Women - Effect of Iodine Supplementation in the Thyroid Function of Mother and Infant

De meest complete database met geneeskrachtige kruiden, ondersteund door de wetenschap