Patients receive the standard medical medication for herpes pain
Oral administration of Gabapentin
300 mg/d on day 1 and 2
600 mg/d on day 3 and 4 if pain persists
900 mg/d on day 5 and 6 if pain persists
Oral administration of Paracetamol up to 3 g per day prescription for 7 day and continue for 3 weeks after evaluation

the patient will receive a regional anaesthesia by Inter fascial block, peripheral nerve block. Local anesthetic used will be ropivacaine 0.5% dose according to the type of block and never exceeding 3mg/kg The type of block would be the most appropriate to cover the dermatomes involved in the Herpes according to the mapping done with the higher ration benefit risks. Choice of Block by an anesthesiologist expert in regional anaesthesia techniques. After the block performance if the pain comes back patient will receive the standard medical treatment as in the group medical treatment

the patient will receive a regional anaesthesia by Inter fascial block, peripheral nerve block. The type of block would be the most appropriate to cover the dermatomes involved in the Herpes according to the mapping done with the higher ratio benefit risks. Local anesthetic used will be ropivacaine 0.5% dose according to the type of block and never exceeding 3mg/kg The choice of the block will be done by an anesthesiologist expert in regional anaesthesia techniques. The block will be repeated every 48h until the pain will reach VAS < 3 6 h after block recovery.

Patients receive the standard medical medication for herpes pain
Oral administration of Gabapentin
300 mg/d on day 1 and 2
600 mg/d on day 3 and 4 if pain persists
900 mg/d on day 5 and 6 if pain persists
Oral administration of Paracetamol up to 3 g per day at day 7 if pain more than VAS 4 the patient will receive a regional anaesthesia by Inter fascial block, peripheral nerve block . Local anesthetic used will be ropivacaine 0.5% dose according to the type of block and never exceeding 3mg/kg The type of block would be the most appropriate to cover the dermatomes involved in the Herpes according to the mapping done with the higher ration benefit risks. Choice of Block by an anesthesiologist expert in regional anaesthesia techniques. After the block performance if the pain comes back patient will receive the standard medical treatment as in the group medical treatment

Patients receive the standard medical medication for herpes pain
Oral administration of Gabapentin
300 mg/d on day 1 and 2
600 mg/d on day 3 and 4 if pain persists
900 mg/d on day 5 and 6 if pain persists
Oral administration of Paracetamol up to 3 g per day prescription for 7 day and continue for 3 weeks after evaluation At day 7 if pain more than VAS 4 the patient will receive a regional anaesthesia by Inter fascial block, peripheral nerve block. The type of block would be the most appropriate to cover the dermatomes involved in the Herpes according to the mapping done with the higher ratio benefit risks. Local anesthetic used will be ropivacaine 0.5% dose according to the type of block and never exceeding 3mg/kg The choice of the block will be done by an anesthesiologist expert in regional anaesthesia techniques. The block will be repeated every 48h until the pain will reach VAS < 3 6 h after block recovery.

Zoster Without Complications

regional anaesthesia by Inter fascial block, peripheral nerve block. The type of block would be the most appropriate to cover the dermatomes involved in the Herpes according to the mapping done with the higher ratio benefit risks. The choice of the block will be done by an anesthesiologist expert in regional anaesthesia techniques. local anesthetic will be ropivacaine 0.5% posology according to the type of block

peripheral nerve block, inter fascial nerve block

Vinmec Health System

Regional Anesthesia to Relief Zoster Pain

Does Repetitive Peripheral Nerve Blocks Vs Single Peripheral Nerve Block Vs Standard Medical Treatment Provide a Better Pain Relief on Zoster Pain at the Acute Phase and Reduce the Risk of Post Herpetic Neuralgia?

Measure by change in the numeric Visual Analogue Scale (VAS) score. The pain-VAS is a single-item scale which is score from 0 -10. A higher score indicates greater pain intensity (0 = "no pain" and 10 = "worst pain imaginable") 0 is the best score 10 is the worse one

PHN is defined as persisting pain beyond the crusting of cutaneous lesion. Pain lasts more than 1 month after the acute infection with the DN4 scale score > 4 and DetectPain scale score > 19

Using the 36-Item Short-Form Health Survey (SF-36) for quality-of-life measurement. Each item is scored on a 0 to 100 range so that the lowest and highest possible scores are 0 and 100, respectively. Higher score defines a more favorable health state.
The overall quality-of-life score at each time-point will be created from all items using an ad-hoc analysis.

The total pain burden is quantified using an area-under-the-curve (AUC) method, using the measures of pain intensity and pain duration. Each patient's AUC is calculated as the sum of all areas obtained by multiplying the average of 2 consecutive pain scores by the number of days between the scores.

Philippe Macaire

Anesthesiologist and Pain physician

Vinmec Healthcare System

Patient randomized in Medical treatment group or Early block group
medical treatment group will have standard pain medications and evaluation of pain relief at day 7
If pain reduce less or egal to VAS 4 medical treatment will continue it will be the control group
If no pain relief VAS more than 4 patient will be randomized to have
single block = Group late block single
or repeated blocks = Group late block repeated
ealy block group will be randomized to have
single block = Group early block single
or repeated blocks = Group early block repeated

maternal blood maternal hair maternal urine umbilical cord blood

Pregnancy

Preeclampsia

this study compares levels of exposure to to fine dust PM 2.5 by individual measurement both at home and at work

amount of fine dust and other environmental exposure

University Hospital Antwerp

Impact of Particulate Matter on Mothers and Babies in Antwerp (IPANEMA)

Impact of Particulate Matter on Mothers and Babies in Antwerp (IPANEMA), a Prospective Cohort Study on the Impact of Pollutants and Particulate Matter in Pregnancy: Methodology and Design

Prof Yves Jacquemyn

Head of Obgyn

Universiteit Antwerpen

A 16 week acupuncture pretreatment followed by letrozole(LE). Acupuncture treatment will start on day 3-5 after a spontaneous period or after a withdrawal bleeding following progestin. All subjects will be requested to use contraception during the 16 week acupuncture pretreatment. They will receive acupuncture treatment three times a week. Each treatment session lasts for 30 minutes and can be separated by an interval of 1-3 days, with a maximum of 48 treatment sessions during 16 weeks. After 16 weeks of acupuncture treatment, LE will start on day 2-3 after a spontaneous period or after a withdrawal bleeding after progestin administration. The subjects will be instructed to have intercourse on a regular basis during the cycles.

LE alone. LE will be started on day 3-5 after a spontaneous period or a withdrawal bleeding following progestin. The subjects will be instructed to have intercourse on a regular basis during the cycles.

Polycystic Ovary Syndrome

Acupuncture treatment will start on day 3-5 after a spontaneous period or after a withdrawal bleeding following progestin. They will receive acupuncture treatment three times a week. Each treatment session lasts for 30 minutes and can be separated by an interval of 1-3 days, with a maximum of 48 treatment sessions during 16 weeks.

Pre-treatment acupuncture

Starting from 2.5mg daily from day 3-5 for 5 days after a spontaneous period or after a withdrawal bleeding following progestin, one time per day.Participants are treated for up to 4 cycles.

Letrozole

The First Affiliated Hospital of Guangzhou Medical University

The Clinical Trial of Acupuncture Pre-treatment on PCOS

Effect of Acupuncture Pre-treatment Combined With Letrozole on Live Birth in Infertile Women With Polycystic Ovary Syndrome

Loss of an intrauterine pregnancy before 20 completed weeks of gestation

Glucose and insulin concentrations, C-peptide, HbA1c, cholesterol, triglycerides, HDL-C and LDL-C

Weight, BMI, waist-to-hip circumference, FG and acne lesion counts

SF-36, ChiQOL, sleeping questionnaires, PCOS-QOL, Zung SAS, Zung SDS questionnaires and the quantization table of TCM syndromes about PCOS.

Hongxia Ma

Professor

The University of Hong Kong

Rhinitis

Sinusitis

Nasal Polyps

Hillel Yaffe Medical Center

The Clinical Efficacy of Topical Nasal Pomegranate Fruit Extract for Patients With Chronic Rhinosinusitis

The Clinical Efficacy of Topical Nasal Pomegranate Fruit Extract (PFE) for Patients With Chronic Rhinitis, Chronic Sinusitis With or Without Nasal Polyps

herpes genitalis/obesitas

Regional Anesthesia to Relief Zoster Pain

Impact of Particulate Matter on Mothers and Babies in Antwerp (IPANEMA)

The Clinical Trial of Acupuncture Pre-treatment on PCOS

The Clinical Efficacy of Topical Nasal Pomegranate Fruit Extract for Patients With Chronic Rhinosinusitis

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