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hypoglycemia/obesitas
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Mammalian glucosidase inhibitors, methods for their use and pharmaceutical compositions thereof
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TECHNICAL FIELD
The present invention relates to methods for inhibiting of alpha-glucosidases in subjects. In particular, the invention relates to the use of human pancreatic alpha-amylase inhibitors to reduce starch hydrolysis in subjects and further relates to the treatment of conditions
Glycoproteins having lipid mobilizing properties and therapeutic uses thereof
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BACKGROUND OF THE INVENTION
Field of the Invention
The present invention relates generally to medicinal formulations and supplements, and more particularly, to formulations and methods for altering the metabolism of a subject, as well as ameliorating disorders such as cachexia, obesity, diabetes and
Targeted oesophageal administration of ZN-.alpha..sub.2-glycoproteins (ZAG), methods and formulations thereof
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BACKGROUND OF THE INVENTION
Field of the Invention
The present invention relates generally to medicinal formulations, and more particularly, to formulations and methods for altering the metabolism of a subject, as well as ameliorating disorders such as obesity, diabetes and insulin
Method of screening substance useful in treating disease with the use of GPR40 and phospholipase
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CROSS REFERENCE TO RELATED APPLICATIONS
The present application is a national phase entry under 35 U.S.C. .sctn.371 of International Application No. PCT/JP2006/320611, filed Oct. 17, 2006, published in Japanese, which claims benefit of Japanese Patent Application No. 2005-321108, filed Nov. 4, 2005.
Compositions and methods for the treatment of metabolic syndrome
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PRIORITY
The present application claims the benefit of Indian Provisional Patent Application No. 1836/CHE/2012 filed on 10 May 2012 and the International Application No. PCT/IB2013/050907 filed on 3 Feb. 2013; the entire disclosure of which is relied on for all purposes and is incorporated into this
Soft protease inhibitors, and pro-soft forms thereof
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BACKGROUND OF THE INVENTION
Proteases are enzymes that cleave proteins at specific peptide bonds. Proteases can be classified into four generic classes: serine, thiol or cysteinyl, acid or aspartyl, and metalloproteases (Cuypers et al., J. Biol. Chem. 1982, 257, 7086. Proteases are essential to a
Aminoalkyl substituted 5,6,7,8-Tetrahydro-9H-Pyridino [2,3-B]indole derivatives
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to aminoalkyl substituted 5,6,7,8-tetrahydro-9H-pyridino[2,3-b]indole and 5,6,7,8-tetrahydro-9H-pyrimidino[4,5-b]indole derivatives, pharmaceutical compositions containing such compounds and their use in treating
Aminoalkyl substituted 5,6,7,8-tetrahydro-9H-pyridino [2, 3-B] indole and 5,6,7,8-tetrahydro-9H-pyrimidino [4, 5-B] indole derivatives: CRF1 specific ligands
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to aminoalkyl substituted 5,6,7,8-tetrahydro-9H-pyridino[2,3-b]indole and 5,6,7,8-tetrahydro-9H-pyrimidino[4,5-b]indole derivatives, pharmaceutical compositions containing such compounds and their use in treating
Imidazopyrimidinyl and imidazopyri dinyl derivatives
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FIELD OF THE INVENTION
The invention presented herein is directed to novel imidazopyrimidinyl and imidazopyridinyl derivatives, and to their use as CRF antagonists in the treatment of a variety of neurological and psychiatric disorders.
BACKGROUND OF THE INVENTION
Corticotropin releasing factor
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