insulinoma/carbohydrate

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[Parameters of carbohydrate metabolism in patients before and after removal of insulinoma].

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Measurements of the daily fluctuations in the sugar blood levels, fasting test, the double glucose tolerance test, and measurements of the blood insulin and C peptide levels were carried out in 13 patients with organic hyperinsulinism prior to insulinoma removal and in the immediate and late periods

[ON INSULOMA AND ITS PECULARITIES IN CARBOHYDRATE METABOLISM].

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[On some features of carbohydrate metabolism in insuloma disease].

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Insulinoma: A Rare Cause of Hypoglycemia in Childhood.

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BACKGROUND Insulinomas are pancreatic neuroendocrine tumors that cause non-ketotic hypoglycemia due to hyperinsulinism; they are extremely rare, especially in children. CASE REPORT We present a case of a sporadic insulinoma in an 11-year-old boy who had episodes of self-limited drowsiness and

[Characteristics of the clinical picture and prognosis of insulinoma].

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A case with insulinoma is reported, with initial malignant degeneration, diagnosed and operated 16 years ago. Six years later hypoglycemic attaks appeared again and lymph metastasis in good health a third surgical operation was performed because of repeated hypoglycemic attacks and a new metastasis

[Clinical picture and prognosis of insulinoma].

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A case of insulinoma is reported, with initial malignant degeneration, diagnosed and operated 16 years ago. Six years later hypoglycemic attacks appeared again and lymph metastasis from malignant degenerated insulinoma were found near to the pancreas. After a period of eight years, in good health

Beta cell response to the hyperglycaemic clamp in three patients with insulinoma: a study using a hyperglycaemic glucose clamp.

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To determine the mechanism responsible for deficient carbohydrate metabolism in patients with insulinoma, we studied three affected patients and seven normal controls using the hyperglycaemic clamp method (8.4 mmol/l) with the BIOSTATOR (GCIIS). In insulinoma patients, the amount of glucose

Inverse relationship between glucose metabolism and glucose-induced insulin secretion in rat insulinoma cells.

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Slowly growing X-ray-induced rat insulinomas and derived cell lines have been used as a model system for glucose-induced insulin release. During perfusions of tumors transplanted under the kidney capsule, the carbohydrates glucose and D-glyceraldehyde increased insulin secretion. These stimuli and

Insulinoma: clinical and diagnostic features of 60 consecutive cases.

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Insulinoma is a rare tumor, occurring more often in women and in the older age range. Eighty percent of patients have a single benign tumor, usually less than or equal to 2 cm in diameter, located with about equal frequency in body, head, or tail of the pancreas and amenable to surgical cure. About

Ketogenic Weight Loss Diet Rapidly Unmasks an Insulinoma.

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The ketogenic diet, a diet high in fat and extremely low in carbohydrates, has recently gained momentum and is increasingly employed by patients in order to lose weight. We report a case of an otherwise healthy 47-year-old male who developed seizures and hypoglycemia shortly after initiating this

[Hypoglycemia caused by insulinoma in diabetes mellitus].

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An hyperglycaemic metabolic state disappeared and spontaneous hypoglycaemia occurred in a 58-year-old woman with non-insulin-dependent obese type II diabetes. Abnormal absence of the hunger response with provoked hypoglycaemia, increased serum insulin concentrations and reduced blood glucose/insulin

The interplay of prolactin and the glucocorticoids in the regulation of beta-cell gene expression, fatty acid oxidation, and glucose-stimulated insulin secretion: implications for carbohydrate metabolism in pregnancy.

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Carbohydrate metabolism in pregnancy reflects the balance between counterregulatory hormones, which induce insulin resistance, and lactogenic hormones, which stimulate beta-cell proliferation and insulin production. Here we explored the interactions of prolactin (PRL) and glucocorticoids in the

Crystalline structures in human pancreatic beta cell adenoma.

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An electron microscopic observation on a pancreatic tumor removed from a 34-year-old woman revealed the fine structural morphology of a functional beta cell adenoma. Characteristic PAS positive crystalline structures were frequently observed in the cytoplasm of the tumor cells. They were not bounded

Multiple beta cell neoplasms in a polar bear: an immunohistochemical study.

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A 25-year-old polar bear had multiple pancreatic islet cell adenomas and carcinomas. Special staining and immunohistochemical techniques showed the neoplasms to be of beta cell origin. An association between excessive carbohydrate diet and the multiple beta cell neoplasms is suggested.

[Peculiarities of the clinical picture, diagnosis and prognosis of insulinoma].

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It is reported on a patient with insulinoma whose diagnosis was made 16 years ago. Operation report: Insulinoma with the histological picture of a little expressed malignant degeneration. After 6 years recidivation of the clinical picture of an insulinoma. Operation report: Metastasis of a malignant

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