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Cancer risk among workers of a secondary aluminium smelter.
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BACKGROUND
Cancer risk in secondary aluminium production is not well described. Workers in this industry are exposed to potentially carcinogenic agents from secondary smelters that reprocess aluminium scrap.
OBJECTIVE
To evaluate cancer risk in workers in a secondary aluminium plant in
Lung and bladder cancer among workers in a Norwegian aluminium reduction plant.
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OBJECTIVE
To investigate the relation between exposure to polycyclic aromatic hydrocarbons (PAHs) and the incidence of lung and bladder cancer among aluminium production workers.
METHODS
The cohort comprised 1790 men employed for more than 5 years at a Norwegian aluminium plant contributing 36 587
[The prevention of tumors in the aluminum industry].
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Aluminium industry workers are exposed to various carcinogenic substances, the most important of which are asbestos and coal pitch and tar fumes. Primary prevention of cancer risk can be achieved either by eliminating the carcinogenic agent from the working environment, or by reducing the exposure
[Mortality in workers of a primary aluminum foundry in Portovesme in Sardinia].
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The standard mortality rates (SMRs) were calculated for 1148 workers of a primary aluminium plant in Portovesme, Sardinia, hired between 1971, when production started, and 1980. Status (living or decreased) was ascertained as at 31 December 1990 and the relationship between observed and expected
Urinary 1-hydroxypyrene as a biomarker of exposure to polycyclic aromatic hydrocarbons: biological monitoring strategies and methodology for determining biological exposure indices for various work environments.
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This article reviews the published studies on urinary 1-hydroxypyrene (1-OHP) as a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs) in work environments. Sampling and analysis strategies as well as a methodology for determining biological exposure indices (BEIs) of 1-OHP in urine for
Mortality of aluminium reduction plant workers in France.
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The mortality between 1950 and 1976 of 6455 French aluminium plant workers was analysed in order to assess occupational risks (especially lung cancer) associated with electrolysis, particularly with the Söderberg process. Mortality from all causes (SMR = 0.85), was lower in this cohort than in the
32P-postlabelling detection of aromatic DNA adducts in peripheral blood lymphocytes from aluminium production plant workers.
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Aluminium production plant workers are exposed to a great number of airborne polycyclic aromatic hydrocarbons and epidemiological studies suggest that these workers are at increased risk of lung and bladder cancer. Blood samples from 46 workers at 2 primary aluminium plants and from 29
Impact of metabolic genotypes on levels of biomarkers of genotoxic exposure.
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Phase I and Phase II xenobiotic-metabolising enzyme families are involved in the metabolic activation and detoxification of various classes of environmental carcinogens. Particular genetic polymorphisms of these enzymes have been shown to influence individual cancer risk. A brief overview is
Intraindividual variations of DNA adduct levels in humans.
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Reports on intraindividual changes of DNA adduct levels in humans are rare. Most of the data available in the literature are from polycyclic aromatic hydrocarbons (PAHs) and are measured in white blood cells with 32P-postlabeling or immunochemical assays. Surprisingly, environmental exposure can
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