Covid-19

Hospital Regional de Alta Especialidad de Ixtapaluca

Association of the Neutrophil/Lymphocyte Ratio With Clinical Complications and Mortality in COVID-19 Patients

Association of the Neutrophil/Lymphocyte Ratio and Lymphocyte /Platelet Ratio With Clinical Complications and Mortality in COVID-19 Patients

To main aim of the study is to evaluate clinical complicatios and mortality in mexican Covid-19 patients

To evaluate the association of the hematological ratios with the clinical complicatios and mortality in covid-19 patinets

To evaluate the differences in hematic and biochemical parameters between survivors and no survivors

To identify the chronic diseases in the patientss´medical records associated with the pulmonary complications

Omar Ramos-Peñafiel

Christian Ramos Peñafiel, MD, PhD

Hospital Regional de Alta especialidad de Ixtapaluca

Hospital General de México Dr. Eduardo Liceaga

Anastomotic Leak

Colorectal Surgery

leakage score (DUtch LeaKage, DULK), that consider several items (fever, heart rate, respiratory rate, urinary production, mental status, clinical conditions, signs of ileus, gastric retention, fascial dehiscence, abdominal pain, wound pain, leukocytosis, CRP, increase of urea or creatinine and nutrition status), to give a score

Dutch score

Serum C-reactive Protein

serum Procalcitonin

UOC Chirurgia Generale - Jesi - AV5 - ASUR Marche

UOC Chirurgia Generale - Ospedale Montichiari (BS) - ASST Spedali Civili di Brescia

Clinica Chirurgica, Università di Brescia - UOC Chirurgia Generale 3, ASST Spedali Civili di Brescia - Brescia

S.C. Chirurgia Generale e Oncologica - Azienda Ospedaliera S. Croce e Carle - Cuneo, Italia

UOC di Chirurgia Addominale IRCCS Casa Sollievo della Sofferenza - San Giovanni Rotondo - Foggia

UOC Chirurgia Generale e Oncologica - Ospedale S. Stefano - Prato (FI) - ASL Toscana Centro

UOC Chirurgia Generale ad Indirizzo Oncologico - IRCCS San Martino IST - Genova

SOC Chirurgia Generale, Oncologica e Vascolare - Azienda Ospedaliera Marche Nord - Pesaro

UOC Chirurgia Generale - Ospedale "Regina Apostolorum" Albano Laziale (RM)

U.O. di Chirurgia Generale e d'Urgenza - Policlinico Casilino - Roma

UOC Chirurgia Generale e Oncologica - Ospedale San Filippo Neri - ASL Roma1

UOS Chirurgia Geriatrica - Policlinico Campus BioMedico - Roma

UOC Chirurgia Generale, Laparoscopica, Toracica -Ospedale "Ceccarini" di Riccione - Area Vasta Romagna

UOC Chirurgia Generale 1 - Ospedale S. Chiara - APSS Trento

UOC Chirurgia Generale - Ospedale "E. Agnelli" di Pinerolo (TO) - ASL TO3

UOC Chirurgia Generale - Ospedale Sacro Cuore Don Calabria Negrar Verona

UOC Chirurgia Generale Oncologica - Azienda Ospedaliera Belcolle - Viterbo

SOC Chirurgia Colorettale - Istituto Nazionale dei Tumori - IRCCS Fondazione "G.Pascale" - Napoli

Early Diagnosis of Anastomotic Leakage After Colorectal Surgery: Italian ColoRectal Anastomotic Leakage Study Group.

Early Diagnosis of Anastomotic Leakage After Colorectal Surgery: a Prospective Observational Validation Study of the Dutch Leakage Score, Serum Procalcitonin and Serum CRP: the Italian ColoRectal Anastomotic Leakage (iCRAL) Study Group.

Main outcome is anastomotic dehiscence (intended as any deviation from the planned postoperative course related to the anastomosis, or presence of pus or enteric contents within the drains, presence of abdominal or pelvic collection in the area of the anastomosis on postoperative CT scan, performed at the discretion of the attending surgeon, leakage of contrast through the anastomosis during enema or evident anastomotic dehiscence at reoperation for postoperative peritonitis). Thus, all detected leaks will be considered independently of clinical significance. No imaging will be performed routinely in order to search for leakage.

Operative morbidity rates, graded according to Clavien-Dindo classification

postoperative length of stay expressed in day(s)

Marco Catarci

Director, General Surgery Unit

Ospedale C & G Mazzoni

Injection, 500 mg, single use, over 15 to 20 minutes.

In Control arm, patients will receive the standardized surgical treatment without receiving methylprednisolone preoperatively (placebo).

Complications

Patients in Methylprednisolone arm will receive injection methylprednisolone 500 mg I/V over 15 to 20 minutes, single dose, 30 minutes before starting surgery.

Methylprednisolone

Patients in the placebo group will receive standard perioperative care and surgery, without preoperative administration of methylprednisolone.

leukocytosis/obesitas

Association of the Neutrophil/Lymphocyte Ratio With Clinical Complications and Mortality in COVID-19 Patients

Early Diagnosis of Anastomotic Leakage After Colorectal Surgery: Italian ColoRectal Anastomotic Leakage Study Group.

Preoperative Glucocorticoid Use in Major Hepatectomy

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