Dutch
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)
10 resultaten
Preferential killing of glucose-depleted HeLa cells by menadione and hyperthermia.
Alleen geregistreerde gebruikers kunnen artikelen vertalen
Log in Schrijf in
Energy deprivation of cancer cells increases sensitivity to killing by hyperthermia. Recent cell culture studies suggest that certain naphthoquinones, especially menadione (vitamin K3), have anti-tumour activity by interfering with the energy metabolism of cells, resulting in the inhibition of
Protocatechuic acid protects against menadione-induced liver damage by up-regulating nuclear erythroid-related factor 2.
Alleen geregistreerde gebruikers kunnen artikelen vertalen
Log in Schrijf in
Menadione (Vitamin K3) is an over-the-counter (OTC) drug used in the treatment of abdominal cramps, colitis, diarrhea, hay fever, hemorrahage, hypoprothrombinemia, and joint pains. In this study, we evaluated the protective influence of protocatechuic acid on menadione-induced
Induction of a 23 kDa stress protein by oxidative and sulfhydryl-reactive agents in mouse peritoneal macrophages.
Alleen geregistreerde gebruikers kunnen artikelen vertalen
Log in Schrijf in
The synthesis of 23 kDa protein was enhanced when mouse peritoneal macrophages were exposed to oxidative agents such as hydrogen peroxide and menadione, or to sulfhydryl-reactive agents such as diethylmaleate, cadmium chloride and sodium arsenite. After 11 h exposure to these agents the 23 kDa
Isolation and preliminary characterization of a Chinese hamster ovary cell line with high-degree resistance to hydrogen peroxide.
Alleen geregistreerde gebruikers kunnen artikelen vertalen
Log in Schrijf in
We have isolated and conducted preliminary characterization of a cell line derived from the Chinese hamster ovary cell line AA8, which we have designated AG8 and which is highly resistant to the cytotoxic effects of H2O2 (approximately 17-fold when the H2O2 treatment was at 37 degrees; approximately
Murine cells transfected with human Hsp27 cDNA resist TNF-induced cytotoxicity.
Alleen geregistreerde gebruikers kunnen artikelen vertalen
Log in Schrijf in
Hyperthermia sensitizes tumor cells to killing by tumor necrosis factor-alpha (TNF). Sensitization is greater in cells exposed to TNF before heating begins than with the reverse sequence, and heat-shock proteins (hsp) have been suggested to protect cells from TNF cytotoxicity. Here we examined the
Vulnerability to oxidative stress in vitro in pathophysiology of mitochondrial short-chain acyl-CoA dehydrogenase deficiency: response to antioxidants.
Alleen geregistreerde gebruikers kunnen artikelen vertalen
Log in Schrijf in
OBJECTIVE
To elucidate the pathophysiology of SCAD deficient patients who have a unique neurological phenotype, among fatty acid oxidation disorders, with early developmental delay, CNS malformations, intractable seizures, myopathy and clinical signs suggesting oxidative stress.
METHODS
We studied
Constitutive expression of human hsp27, Drosophila hsp27, or human alpha B-crystallin confers resistance to TNF- and oxidative stress-induced cytotoxicity in stably transfected murine L929 fibroblasts.
Alleen geregistreerde gebruikers kunnen artikelen vertalen
Log in Schrijf in
Hyperthermia and other forms of stress that induce and/or stimulate heat shock or stress protein (hsp) expression enhance the cellular resistance to TNF-alpha. One of the stress proteins, hsp70, has been shown to participate in the molecular mechanisms that regulate this phenomenon. Here we have
Inducible and constitutive HSP70s confer synergistic resistance against metabolic challenges.
Alleen geregistreerde gebruikers kunnen artikelen vertalen
Log in Schrijf in
Chaperonic proteins, including inducible HSP70 (HSP70i) and constitutive HSP70 (HSC70), have been implicated as essential players in the cellular adaptive protection. Ensuing studies demonstrated that overexpression of either protein individually protects against thermal and oxidative challenges.
Oxidants differentially regulate the heat shock response.
Alleen geregistreerde gebruikers kunnen artikelen vertalen
Log in Schrijf in
Cells, animals, and humans respond to hyperthermia through the synthesis of a family of proteins termed heat shock proteins (HSPs). Because hyperthermic stress may also result in mitochondrial uncoupling and the generation of reactive oxygen species, we wondered whether oxidant stress was sufficient
Multiple cellular effects of leaf extracts from Parinari curatellifolia.
Alleen geregistreerde gebruikers kunnen artikelen vertalen
Log in Schrijf in
BACKGROUND
Parinari curatellifolia is a prominent plant in folk medicine in Sub-Saharan Africa. The plant decoctions are used to treat various ailments, including the treatment of cancer, pneumonia, fever, microbial infections and anti-inflammation. The aims of the study were to investigate the
De meest complete database met geneeskrachtige kruiden, ondersteund door de wetenschap
- Werkt in 55 talen
- Kruidengeneesmiddelen gesteund door de wetenschap
- Kruidenherkenning door beeld
- Interactieve GPS-kaart - tag kruiden op locatie (binnenkort beschikbaar)
- Lees wetenschappelijke publicaties met betrekking tot uw zoekopdracht
- Zoek medicinale kruiden op hun effecten
- Organiseer uw interesses en blijf op de hoogte van nieuwsonderzoek, klinische onderzoeken en patenten
Typ een symptoom of een ziekte en lees over kruiden die kunnen helpen, typ een kruid en zie ziekten en symptomen waartegen het wordt gebruikt.
* Alle informatie is gebaseerd op gepubliceerd wetenschappelijk onderzoek
